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Testing a Surgical Device for Removing Ovarian Cyst Lesions

Studies a surgical device to remove endometriosis cyst tissue from ovaries while sparing healthy tissue.

Key facts

Who runs it
Kanazawa University
Where
Kanazawa, JapanSee the site
Trial code
Registry title
Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas
Status
Recruiting
People taking part
10 people, planned
Started
30 Jan 2025
Expected to end
31 Mar 2028
Type of study
Observational
Treatments tested
  • Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity
Record updated
10 October 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women aged 20 or older with an ovarian endometrioma who are having surgery at Kanazawa University Hospital. The removed cyst tissue is tested in the lab with a new ultrasonic surgical device.

Age
20 years or older
Sex
Women only
Disease stage
Ovarian endometrioma that is treated by surgery (cystectomy or adnexectomy)

Main reasons for not taking part

  • Suspected cancer on scans taken before surgery
  • The treating doctor judges the person unsuitable for the study for any reason
  • No written informed consent

The registry criteria, word for word

Show all 6 criteriaShow less

Who can take part

  • Female patients diagnosed with ovarian endometrioma who undergo surgical treatment (cystectomy or adnexectomy) at Kanazawa University Hospital between January 1, 2025, and March 31, 2027
  • Written informed consent obtained prior to study participation
  • Age ≥ 20 years at the time of consent
  • For patients with previously stored endometrioma specimens under a broad consent, additional written consent for participation in this study will be obtained

Who cannot take part

  • Patients with suspected malignancy based on preoperative imaging
  • Patients judged by the attending physician to be unsuitable for participation in this study for any reason

Where in Japan

  • Kanazawa University HospitalKanazawa, JapanContact: Tatsuhito Kanda, MD, PhDTaking people

About the trial

What the trial wants to find out

This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas. Ovarian endometriomas are cysts caused by endometriosis that can damage ovarian reserve when treated by conventional surgery. In this study, ovarian cyst wall specimens are examined ex vivo using different Tissue Select settings of the CUSA device. Histopathological analyses are performed to determine whether endometriotic epithelium can be selectively removed while preserving normal ovarian tissue. The findings may contribute to developing fertility-preserving surgical approaches for women with endometriomas.

The group in the trial

  • Ovarian Endometrioma Cases

    Patients with ovarian endometriomas undergoing surgical excision at Kanazawa University Hospital. Cyst wall specimens are collected and analyzed ex vivo using the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity device at different Tissue Select settings. Histopathological evaluation is performed to assess selective removal of endometriotic epithelium and preservation of ovarian stroma.

    Treatment: Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas: A Case-Based Histopathological Study
Plain-language title
Testing a Surgical Device for Removing Ovarian Cyst LesionsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
10 October 2025