Studying sleep and mental health after brain injury from stroke or trauma
Tracks sleep and mental health in adults with brain injury over one year.
Plain-language title generated from the registry record
Registry title: Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury
Key facts
- Where
- Oxford, United KingdomSee the site
Where in United Kingdom
- Oxford Centre for Integrative Neuroimaging (WIN) FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford OX3 9DUOxford, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Oxford
- Trial code
- NCT07215195
- Record updated
- 9 November 2026
- Original description
The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse mental health in this group. We will also follow patients up, at approximately three-monthly intervals until one year after injury, to see how sleep and mental health symptoms change over time and with recovery.Read full original descriptionShow less
Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury
The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse mental health in this group. We will also follow patients up, at approximately three-monthly intervals until one year after injury, to see how sleep and mental health symptoms change over time and with recovery.
We will assess sleep in detail using questionnaires, a sleep monitor worn on the wrist, a portable brain activity sensor, and a sleep mat. We will assess mental health (neuropsychiatric) symptoms using questionnaires.
Participants will be asked to complete these assessments at baseline and at approximately 3-monthly intervals until they reach 12 months post-injury.
This data will allow us to explore the types of sleep disruption seen after brain injury and examine the association between sleep and mental health symptoms.
Inclusion: Willing and able to give informed consent for participation in the study; Aged 18 years or above; At least one week, but less than 12 months post-injury; Clinical diagnosis of acquired brain injury (stroke, haemorrhage or traumatic); Participants with Traumatic Brain Injury will have a Mild (probable) or Moderate-severe (definite) brain injury according to the Mayo classification; Participants must be willing to consent to us contacting their general practitioner (GP) or direct care team if we have concerns about their mental health.
Exclusion: Previous brain injury; Brain injury not caused by trauma, haemorrhage or stroke; Other relevant neurological conditions which could affect outcome measures (e.g., Parkinson's or Alzheimer's disease); No stable and suitable place to sleep.