NCT07217158Active, not recruiting
Role of ROS and cAMP-PKA Biomarkers in ADPKD
Role of ROS and cAMP-PKA Signaling-related Biomarkers on Renal Disease Severity and Progression in ADPKD
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
The primary objective is to determine the prognostic value of markers of ROS and cAMP-PKA signaling to assess disease severity and progression in patients with ADPKD.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 100 (actual)
- First submitted
- 13 Oct 2025
- Start date
- 1 Jul 2023
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Mayo Clinic
- Diseases
- Polycystic kidney disease
- NCT number
- NCT07217158
What you commit to
- Study type: Observational
- Participants enrolled: 100
- From 1 Jul 2023 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- A concomitant systemic disease affecting the kidney
Other illness
- Diabetes mellitus
Other
- Class 2, according to imaging classification
- Predicted urine protein excretion in \>1 g/24 hrs. and or abnormal urinalysis
- Use of antioxidants, i.e., vitamins, Nrf2 activators
- Patients who are part of an interventional study or taking tolvaptan
Who the study is looking for
- Male and female subjects 15 - 70 years of age
- Previous diagnosis of ADPKD (based on Ravine et al. criteria)
- Class 1 A-E according to imaging classification
- estimated GFR\> 45 mL/min/1.73 m2 (CKD-EPI)
- Ability to provide written, informed consent
Age in the registry: 15 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.