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Taking peoplePhase 4

Long-term safety of pirtobrutinib in people with chronic lymphocytic leukemia

Studies long-term safety of pirtobrutinib in adults with previously treated leukemia or lymphoma.

Plain-language title generated from the registry record
Registry title: A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Key facts

Where
Santander and Seville, SpainSee the 2 sites
Phase
Phase 4

Where in Spain

  • Hospital Universitario Marqués de ValdecillaSantander, SpainNot yet recruiting
  • Hospital Universitario Virgen del RocioSeville, SpainNot yet recruiting

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Eli Lilly and Company
Trial code
NCT07218341
Record updated
4 November 2026
Original description
This study will evaluate the long-term safety of pirtobrutinib in participants with previously treated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study is open to those who completed J2N-MC-JZNN/LOXO-BTK-20020 (NCT 04666038) for continued access to the study intervention or continued follow-up visits. Treatment will be given every 4 weeks and this study is expected to last about 5 years.Read full original descriptionShow less

Long-Term Safety of Pirtobrutinib in Participants From Study LOXO-BTK-20020 With BTKi Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

This study will evaluate the long-term safety of pirtobrutinib in participants with previously treated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study is open to those who completed J2N-MC-JZNN/LOXO-BTK-20020 (NCT 04666038) for continued access to the study intervention or continued follow-up visits. Treatment will be given every 4 weeks and this study is expected to last about 5 years.

Inclusion: Are actively participating in study J2N-MC-JZNN/LOXO-BTK-20020.

Exclusion: This is not applicable to this study.

ClinicalTrials.gov NCT07218341