Testing Brenipatide Against Placebo for Uncontrolled Asthma in Adults
Tests brenipatide at different doses against placebo in adults with moderate to severe asthma.
Plain-language title generated from the registry record
Registry title: A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Key facts
- Where
- Buenos Aires, Ciudad de Buenos Aires, Corrientes, Granadero Baigorria, Mar del Plata, Río Cuarto, Rosario, and Santa Fe, ArgentinaSee the 10 sites
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07219173, who can take part
Where in Argentina
- Centro de Investigaciones Metabólicas (CINME)Buenos Aires, ArgentinaTaking people
- Consultorios Médicos, Organización del Buen Ayre S.R.L.Buenos Aires, ArgentinaTaking people
- Fundacion RespirarBuenos Aires, ArgentinaTaking people
- IDIM - Instituto de Investigaciones MetabólicasCiudad de Buenos Aires, ArgentinaTaking people
- Instituto de Asma, Alergia y Enfermedades RespiratoriasCorrientes, ArgentinaTaking people
- Centro de Investigaciones Clínicas BaigorriaGranadero Baigorria, ArgentinaTaking people
- Instituto de Investigaciones Clinicas Mar del PlataMar del Plata, ArgentinaTaking people
- Instituto Médico Río CuartoRío Cuarto, ArgentinaTaking people
- ABC Instituto de DiagnósticoRosario, ArgentinaTaking people
- IbamedicaSanta Fe, ArgentinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Eli Lilly and Company
- Trial code
- NCT07219173
- Record updated
- 5 November 2026
- Original description
The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma.Read full original descriptionShow less
A Phase 2, Multicenter, Randomized, Double-blind, 52-week Study, to Investigate the Efficacy and Safety of Brenipatide Compared With Placebo for the Treatment of Adult Participants With Uncontrolled Moderate to Severe Asthma
The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma.
Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.
Inclusion: Physician-diagnosed asthma who have received a physician-prescribed asthma controller medication for at least 12 months prior to screening visit; Participants must have an asthma control questionnaire-6 (ACQ-6) score of ≥1.5 on 2 out of 3 visits before randomization; History of 1 severe asthma exacerbation that led to systemic glucocorticoid treatment in the last 12 months prior to screening visit.
Exclusion: Have a current or recent acute, active infection. For at least 30 days before screening visit and up to the randomization visit; Known pre-existing, clinically important lung condition other than asthma, including but not limited to:; chronic respiratory infection; bronchiectasis; pulmonary fibrosis; allergic bronchopulmonary aspergillosis; emphysema; chronic bronchitis; eosinophilic granulomatosis with polyangiitis; chronic obstructive pulmonary disease, and; other mimics of asthma, that is, vocal cord dysfunction; Participants are excluded from the study if any of the following criteria apply:; An established diagnosis of occupational asthma.