NCT07219537Recruiting
A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
Pilot Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
The investigators have developed an inexpensive tool to take pictures in the lower GI tract without sedation and to look for signs of disease. The tool is a capsule, about the size of a fish oil or multi-vitamin supplement, attached to a string. The capsule and string are connected to a motor to allow the capsule to advance up the participant's lower GI tract. The capsule will be inserted into the participant's lower GI tract and advance upward via a slow spiral motion. The capsule is connected to an imaging system that saves and displays the images in real time.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 20 Oct 2025
- Start date
- 27 Mar 2023
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Crohn's disease
- NCT number
- NCT07219537
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 27 Mar 2023 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Who currently use drugs that interfere with coagulation (excluding low-dose aspirin)
- With any prior anorectal, colorectal, or colonic surgery
Other illness
- With a current diagnosis of any bleeding disorders
- With a history or current diagnosis of colorectal cancer
- With a history of volvulus or torsion
- With severe acute inflammatory bowel disease
- With large hemorrhoids or hemorrhoidal bleeding or banding
Age
- Who are over 75 years of age or older
Other
- With a history or current diagnosis of colonic and/or anal strictures
- With a history or current diagnosis of diverticulosis or diverticulitis
- Who are pregnant
- With contraindications to bowel prep or colonoscopy
Who the study is looking for
- Are 18 years of age or older.
- Are healthy or with a confirmed diagnosis of Lynch Syndrome
- Are capable of giving informed consent.
- Are able to follow bowel prep instructions
- Had a colonoscopy 0-24 months prior that did not show any abnormalities or individuals who report no gastrointestinal symptoms and no knowledge of any lower GI tract disease or abnormality and volunteer through Rally.
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.