NCT07222930Enrolling by invitation
Learning Amyloid and Tau Results
Reactions to Learning Amyloid and Tau Results in Adults at Risk for Alzheimer's Dementia
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
This is a prospective, single-cohort, single-center, observational study to assess if learning one's Alzheimer's disease biomarker test result impacts longitudinal psychosocial, behavioral, and neuropsychological outcomes, and to identify factors that moderate and mediate these outcomes. Participants enrolled in this study are requested to complete surveys at four timepoints after learning their Alzheimer's biomarker test results.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 240 (estimated)
- First submitted
- 29 Oct 2025
- Start date
- 17 Feb 2026
- Primary completion date
- Jun 2029
- Lead sponsor
- University of Wisconsin, Madison
- Diseases
- Frontotemporal dementia, Alzheimer disease
- NCT number
- NCT07222930
What you commit to
- Study type: Observational
- Planned participants: 240
- From 17 Feb 2026 to the primary completion date, Jun 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosis of dementia at the time of enrollment as determined by the most recent parent WRAP/ADRC study visit diagnostic consensus conference using standard NIA-AA 2011 diagnostic criteria. Participants who develop dementia after enrolling into this study may remain enrolled if they maintain decisional capacity and are able to follow study instructions and procedures.
Other
- Individuals who lack decisional capacity to provide informed consent as determined by significant difficulty in understanding materials and information about study procedures during recruitment and/or informed consent discussions.
- Not suitable for study participation due to other reasons at the discretion of the investigators.
Who the study is looking for
- Willing to provide informed consent.
- Willing to comply with all study procedures and be available for the duration of the study.
- Individuals at least 45 years of age.
- Enrolled in Wisconsin Registry for Alzheimer's Prevention (WRAP) or Alzheimer's Disease Research Center Clinical Core (ADRC)
- Previously adjudicated as cognitively unimpaired having mild cognitive impairment (MCI), or impaired but do not meet diagnostic criteria for mild cognitive impairment or dementia (classified as "Impaired-Not MCI" by the WRAP and ADRC cohorts) at their last WRAP or ADRC study visit at the time of enrollment into this study
- Have completed or able to complete amyloid and/or tau PET scans as part of a UW Alzheimer's Research Study
Age in the registry: 45 years to 89 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Wisconsin Coordinator of this site? Confirm its status | Madison | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.