Meaning-based talk therapy for Mexican adults living with advanced cancer
Tests a meaning-centered talk therapy for anxiety and depression in Mexican adults with advanced cancer.
Plain-language title generated from the registry record
Registry title: A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
Key facts
- Where
- Mexico City, MexicoSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with stage III or IV breast, prostate, colorectal, thyroid, cervical, uterine or lung cancer treated at INCan, and for providers who deliver the therapy. It tests talk therapy for anxiety and depression.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Stage III or IV solid tumor cancer (breast, prostate, colorectal, thyroid, cervix, uteri or lung), confirmed by pathology, with a recent or new diagnosis
- Earlier treatment
- Must be receiving outpatient care at INCan. Cannot have had psychological or psychiatric care in the last 3 months.
Main reasons for not taking part
- Psychological or psychiatric care in the last 3 months, at INCan or elsewhere
- Serious psychiatric condition
- Cognitive impairment such as delirium or dementia that prevents informed consent
- Risk of suicide on the Columbia-Suicide Severity Rating Scale
- Too ill to take part
Read by machine on 9 November 2026.
Where in Mexico
- Instituto Nacional de Cancerología (INCan)Mexico City, MexicoNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Memorial Sloan Kettering Cancer Center
- Trial code
- NCT07225309
- Record updated
- 3 August 2026
- Original description
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.Read full original descriptionShow less
Trial of Meaning Centered Psychotherapy for Mexican Patients With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.
Inclusion: EMR Criteria; Documentation of Disease; Pathologically confirmed breast, prostate, colorectal, thyroid, cervix, uteri, or lung - solid tumor cancer (either most recent or new diagnosis); Definition of Disease [or Measurable Disease]; Diagnosed with stages III or IV; Prior Treatment; Receiving ambulatory care at INCan; Self-Report Criteria; Age ≥ 18 years; Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"; Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention; Providing care (or services) to Mexican cancer patients at INCan; Has access to internet and an electronic device; Agrees to be audio-recorded; Age ≥ 18 years; Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"; Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention; Providing care (or services) to Mexican cancer patients at INCan; Has access to internet and an electronic device; Agrees to be audio-recorded.
Exclusion: Prior Treatment; Received psychological or psychiatric care at INCan in the last 3 months; In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation; Diagnosed with a serious psychiatric condition; Self-Report Criteria; Received psychological or psychiatric care outside of INCan in the last 3 months; EMR Criteria; Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale; Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"; Provider Eligibility Criteria:.
Patient Eligibility Criteria:; A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener and suicide risk assessment.