Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)
Key facts
- Where
- La Romana, Dominican RepublicSee the site
Where in Dominican Republic
- Clínica de Familia La RomanaLa Romana, Dominican RepublicTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Columbia University
- Trial code
- NCT07225530
- Record updated
- 25 February 2026
- Original description
This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic. With cervical cancer being a leading cause of cancer-related deaths in women living with HIV, and cervical cancer deaths being preventable through screening and early detection, this project seeks to identify factors associated with the successful implementation of the Screen, Triage, and Treat approach to inform future implementation and scale-up.Read full original descriptionShow less
This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic. With cervical cancer being a leading cause of cancer-related deaths in women living with HIV, and cervical cancer deaths being preventable through screening and early detection, this project seeks to identify factors associated with the successful implementation of the Screen, Triage, and Treat approach to inform future implementation and scale-up.
Inclusion: 25 years of age; female sex assigned at birth (any gender identity); HIV-positive; women who have had cervical cancer precursor lesions which were removed more than 6 months ago; and; understand Spanish.
Exclusion: previous diagnosis of gynecological cancer; history of a Loop Electrosurgical Excision Procedure (LEEP) procedure in the last 6 months; history of a hysterectomy; history of cancer of the anogenital tract; or; ages outside of the specified inclusion criteria; women who are pregnant, less than 6 weeks postpartum, or in whom pregnancy cannot be excluded; unable or unwilling to provide informed consent.