Walking Training With Spinal Stimulation for Non-Walking Stroke Survivors
Tests robot-assisted walking training with spinal cord stimulation in chronic stroke survivors who cannot walk.
Plain-language title generated from the registry record
Registry title: Walking and tSCS in Non-ambulatory Stroke Survivors
Key facts
- Where
- Kansas City, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07226518, who can take part
Where in United States
- Neuromuscular Research LaboratoryKansas City, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Kansas Medical Center
- Trial code
- NCT07226518
- Record updated
- 10 November 2025
- Original description
Rehabilitation interventions commonly used for stroke survivors include task-specific training, balance and strength exercises, and the use of assistive devices to enhance mobility and independence. Advanced technologies, such as body-weight-supported treadmill systems and robotic devices, may be employed when appropriate. Current rehabilitation therapies for stroke survivors are moderately effective with a limited effect size, especially in stroke survivors with severe impairment. Novel therapies, such as transcutaneous spinal cord stimulation (tSCS), may further improve outcomes in the target population. This pilot study will allow us to examine the feasibility and gather pilot data on a combined intervention of assistive gait training and tSCS in non-ambulatory stroke survivors.Read full original descriptionShow less
Robot-assisted Gait Training and Transcutaneous Spinal Cord Stimulation in Chronic Non-ambulatory Stroke Survivors: Pilot RCT Trial
Rehabilitation interventions commonly used for stroke survivors include task-specific training, balance and strength exercises, and the use of assistive devices to enhance mobility and independence. Advanced technologies, such as body-weight-supported treadmill systems and robotic devices, may be employed when appropriate. Current rehabilitation therapies for stroke survivors are moderately effective with a limited effect size, especially in stroke survivors with severe impairment. Novel therapies, such as transcutaneous spinal cord stimulation (tSCS), may further improve outcomes in the target population. This pilot study will allow us to examine the feasibility and gather pilot data on a combined intervention of assistive gait training and tSCS in non-ambulatory stroke survivors.
Inclusion: Age 18-80 years at time of consent; All genders included; Chronic ischemic or hemorrhagic stroke >=6 months, with limited within-home comfortable walking speed <= 0.49 m/s and unable to walk independently in community (FAC <= 3); Able to communicate with investigators, follow 2-step command, and correctly answer consent comprehension questions in English; Currently not participating in treadmill walking exercises or exercises involving weight-bearing activities; Have physicians' approval for exercise and be in a stable medical condition.
Exclusion: Hospitalization for cardiac or pulmonary disease within the past 3 months; Have musculoskeletal disorders that prevent the participant from participating in the exercise; Significant ataxia or unilateral spatial neglect (score of 2 on NIH stroke scale item 7 or 11); Diagnosis of other neurological diseases (multiple sclerosis, Alzheimer's disease, Parkinson's disease); Unable to speak or understand English, and travel to the research laboratory; Blood pressure higher than 200/110 mm Hg; Reported pain that limits or interferes with activities of daily living and physical activity/exercise; Diagnosis of severe depression (HADS score 15-21); Contraindications to tSCS and TMS.