Measuring Calcium Deposits in Skin Using CT Scans in Systemic Sclerosis
Tests CT scan measurements of skin calcium deposits in adults with systemic sclerosis.
Plain-language title generated from the registry record
Registry title: Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Key facts
- Where
- New Haven, United StatesSee the site
Where in United States
- Yale Scleroderma ProgramNew Haven, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Yale University
- Trial code
- NCT07228429
- Record updated
- 4 November 2026
- Original description
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.Read full original descriptionShow less
Quantification of Calcinosis Cutis Disease Burden in Patients With Systemic Sclerosis Using Computed Tomography Images
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.
Inclusion: Scleroderma/systemic sclerosis patient with diagnosed calcinosis cutis who will be clinically treated with STS as they would in clinical SOC care; Must be ≥ 18 years old and meet the 2013 American College of Rheumatology criteria for the diagnosis of systemic sclerosis (diffuse or limited); Receiving clinical care at Yale clinics.
Exclusion: Unable to provide informed consent; Currently pregnant or nursing; Patients with a calcinosis ROI >6cm.