Under construction – not a live service
Sign in
CompletedNo phase

Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss

Key facts

Who runs it
Istanbul University - Cerrahpasa
Where
Türkiye1 site in 1 countryChoose a country to see its sites
Trial code
Status
Completed
People taking part
66 people enrolled
Started
20 Aug 2025
Ended
15 May 2026
Type of study
Observational, 3 groups
Record updated
6 October 2026

Who can take part

Age
20 years to 60 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 25 criteriaShow less

Who can take part

  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having no tinnitus or auditory complaints,
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests
  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having a chronic tinnitus complaint (≥3 months),
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests
  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having no chronic tinnitus complaint,
  • Having an average score below 4.3 on the "Speech Perception" subscale of the Speech, Spatial and Qualities of Hearing Scale (SSQ),
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests

Who cannot take part

  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests
  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests
  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology. Therefore, it is suggested that low-spontaneous-rate auditory nerve fibers are damaged in HHL. Consequently, LS CE-Chirp-evoked ABR and HINT, which assesses CS by presenting stimuli of varying intensities and characteristics to provide information about auditory nerve fibers, will be used to evaluate participants both objectively and subjectively.

Read full original descriptionShow less

Aim of the study:

The main aim of this study is to investigate the relationship between the amplitude and latency values obtained with LS CE-Chirp-stimulated ABR and the critical Signal-to-Noise Ratio (SNR) obtained from the Hearing in Noise Test (HINT) in individuals suspected of having HHL.

Hypotheses

H0: In individuals suspected of having HHL, there is no relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio and the critical SNR obtained from HINT.

H1: In individuals suspected of having HHL, there is a relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio, and the critical SNR obtained from HINT.

Expected Results:

The study will reveal how LS CE-Chirp stimulation affects ABR results in individuals suspected of having HHL, and the relationship between these results and HINT results will be examined. In this way, HHL will be evaluated both objectively (LS CE-Chirp ABR) and subjectively (HINT). Based on the findings, scientific outputs such as publications or projects are targeted.

Importance:

HHL has recently attracted increasing attention as a condition that significantly affects daily life. In today's world, where noise and noisy environments are prevalent, disadvantages arise in many aspects, particularly in communication. Therefore, the findings obtained in this study may contribute to a better understanding of HHL.

The 3 groups in the trial

  • Control group

    Inclusion Criteria Being between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having no tinnitus or auditory complaints, Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests. Exclusion Criteria Presence of peripheral and/or central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and/or neurological problems that could interfere with the tests.

  • First study group

    Inclusion Criteria Being between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having a chronic tinnitus complaint (≥3 months), Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests. Exclusion Criteria Presence of peripheral and/or central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and/or neurological problems that could interfere with the tests.

  • Second study group

    Inclusion Criteria Being between 20 and 60 years of age, Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL), Having no chronic tinnitus complaint, The mean scores on the questions assessing the ability to understand speech in noise in the "Speech Perception" subscale of the SSQ (Speech, Spatial, and Hearing Quality Scale) are below the normative value, Scoring 21 or above on the MoCA test, Having no emotional or neurological problems that could interfere with the tests. Exclusion Criteria Presence of peripheral and/or central hearing loss, Presence of somatosensory tinnitus, Presence of emotional and/or neurological problems that could interfere with the tests.

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Investigation of the Relationship Between LS Chirp ABR and Comprehension In Noise Skills In Individuals With Suspected Hidden Hearing Loss
Record updated
6 October 2026