NCT07232225Not yet recruiting
OCT-Based Screening for Early Retinal Changes in Asymptomatic Diabetic Patients
Source: ClinicalTrials.gov · Last updated 18 Nov 2025
Brief summary (registry, in English)
The goal of this observational study is to detect early retinal changes in people with diabetes who do not have visual symptoms. The study will use Optical Coherence Tomography (OCT) and fundus examination to screen for early retinal involvement in diabetic patients. The main questions this study aims to answer are: Can OCT detect early retinal changes before symptoms appear in people with diabetes? Is fundus examination useful for identifying early diabetic retinal changes? Participants will undergo a comprehensive eye examination, including OCT macular scans and fundus examination, at Assiut Ophthalmology Hospital. No treatment or invasive procedures will be performed as part of this study. The collected data will help improve early detection and prevention of diabetic retinal complications.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 112 (estimated)
- First submitted
- 14 Nov 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Assiut University
- Diseases
- Diabetic eye disease
- NCT number
- NCT07232225
What you commit to
- Study type: Observational
- Planned participants: 112
- From 1 Dec 2025 to the primary completion date, 1 Dec 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of previous macular disease or treatment (laser photocoagulation or intravitreal injection)
Other illness
- Systemic or neurological diseases that affect the retina or visual pathway
Age
- Presence of other retinal diseases (e.g., age-related macular degeneration, retinal vein occlusion)
Other
- Media opacity that prevents adequate OCT imaging (e.g., dense cataract, corneal opacity)
- Uncooperative participants or those who decline to give consent
Who the study is looking for
- Confirmed diagnosis of type 1 or type 2 diabetes mellitus for at least 6 months
- Best-corrected visual acuity (BCVA) of 6/6 using Snellen chart
- No visual symptoms (no blurred vision or metamorphopsia)
- Clear ocular media allowing high-quality OCT imaging
- No significant abnormalities on fundus examination
- Intraocular pressure (IOP) below 21 mmHg
- Willing and able to provide written informed consent
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.