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Studying memory, thinking skills and mood in adults with migraine

Describes thinking skills and mood in adults with migraine and links to their treatment.

Plain-language title generated from the registry record
Registry title: Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables

Key facts

Where
Milan, ItalySee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 18 to 65 with migraine, to describe how their thinking and mental skills work and how this relates to mood and worry.

Age
18 to 65 years
Sex
All sexes
Disease stage
Migraine diagnosed by ICHD-3 criteria, present for at least one year
Earlier treatment
Ongoing treatment must have been stable for at least 3 months

Main reasons for not taking part

  • Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) with a documented diagnosis
  • A history of alcohol or drug abuse
  • Primary sensory deficits

Read by machine on 12 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07233941, who can take part

Where in Italy

  • Fondazione IRCCS Istituto Neurologico Carlo BestaMilan, ItalyContact: Danilo A Montisano, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Trial code
NCT07233941
Record updated
11 February 2026
Original description
The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.Read full original descriptionShow less

Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.

Inclusion: Written informed consent; Patients aged between 18 and 65 years; Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria; Patients with a history of migraine for at least one year, to ensure the stability of the condition; Stability of ongoing treatment for at least 3 months at baseline; Understanding of the Italian language.

Exclusion: Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses; A history of alcohol or drug abuse; Primary sensory deficits.

ClinicalTrials.gov NCT07233941