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Searching for Biological Markers in People With Neurodegenerative Diseases Such as Alzheimer's and Parkinson's

Studies genes, proteins and other body markers in adults with neurodegenerative diseases.

Plain-language title generated from the registry record
Registry title: Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

Key facts

Where
Genoa, ItalySee the site

Where in Italy

  • Ospedale Policlinico San MartinoGenoa, ItalyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Ospedale Policlinico San Martino
Trial code
NCT07235111
Record updated
25 November 2025
Original description
The study aims to use 'omics' sciences, employing the most advanced technologies currently available, in order to identify pathogenic genomic variants, proteins and/or altered molecular pathways in neurodegenerative diseases and to obtain a new and more complete characterisation of subjects affected by the neurodegenerative diseases under study. Thanks to the integration of genomic, gene expression (transcriptomic and epigenomic), protein and metabolic data and clinical data, the study also aims to identify new markers for the diagnosis, prognosis, also in terms of response to therapy, and monitoring of neurodegenerative diseases.Read full original descriptionShow less

Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

The study aims to use 'omics' sciences, employing the most advanced technologies currently available, in order to identify pathogenic genomic variants, proteins and/or altered molecular pathways in neurodegenerative diseases and to obtain a new and more complete characterisation of subjects affected by the neurodegenerative diseases under study. Thanks to the integration of genomic, gene expression (transcriptomic and epigenomic), protein and metabolic data and clinical data, the study also aims to identify new markers for the diagnosis, prognosis, also in terms of response to therapy, and monitoring of neurodegenerative diseases.

The study involves the enrolment of at least 1.200 individuals with neurodegenerative disease.

Inclusion: Patients suffering from neurodegenerative diseases.

Exclusion: Patients not suffering from neurodegenerative diseases.

ClinicalTrials.gov NCT07235111