Brain Stimulation With Gait Training for Stroke Recovery
Tests brain stimulation with walking and thinking training in adults after stroke.
Plain-language title generated from the registry record
Registry title: Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals
Key facts
- Where
- Nakhon Pathom, ThailandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07236216, who can take part
Where in Thailand
- Faculty of Physical Therapy, Mahidol UniversityNakhon Pathom, ThailandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mahidol University
- Trial code
- NCT07236216
- Record updated
- 23 February 2026
- Original description
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dual task gait training in sub-acute (at least 2 weeks after stroke onset) to chronic (within 5 years post-stroke) to investigate the effect on cortical activity, spinal motoneuron excitability, cognition and motor performance. The findings may enhance the evidence to support usages of tES for improvimg cognition, motor performance as well as cortical activity and spinal motoneuron excitability in a clinical setting.Read full original descriptionShow less
Effects of Transcranial Electrical Stimulation (tES) Combined With Cognitive-motor Dual-task Gait Training on Cortical Activity, Spinal Motoneuron Excitability, Cognition and Motor Performance in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dual task gait training in sub-acute (at least 2 weeks after stroke onset) to chronic (within 5 years post-stroke) to investigate the effect on cortical activity, spinal motoneuron excitability, cognition and motor performance. The findings may enhance the evidence to support usages of tES for improvimg cognition, motor performance as well as cortical activity and spinal motoneuron excitability in a clinical setting.
Inclusion: Unilateral stroke individuals aged 18-80 years; A first-ever stroke; Stroke onset from at least 2 weeks-5 years; Able to walk independently with or without gait aids (modified Rankin scale (mRS) 1-3); Montreal cognitive Assessment-Thai version (MoCA-T) greater than or equal to 20 scores; Ability to read, communicate, follow and understand instructions.
Exclusion: Receiving other non-invasive brain stimulation or additional intervention such as TMS, PMS or acupuncture; Presence of any psychological or neurological antecedent, unstable medical conditions or condition that may increase risk of stimulation such as epilepsy, seizure, and history of brain injury; Having unstable cardiovascular disease or respiratory disease, and uncontrolled chronic disease such as diabetes mellitus (DM), hypertension (HT) and chronic kidney disease (CKD); Presence of metal implantation, intracranial shunt, cochlear implantation, or cardiac pacemakers; Presence of an opened wound, infectious wound around scalp or craniectomy with unreplaced bone flap; Moderate pain (numeric pain rating score > 4/10) in any joint of the upper or lower limb, whether paretic or non-paretic; Presence of color blindness; Presence of any substance use including cannabis and kratom.