Effectiveness of Modified Constraint-Induced Movement Therapy Delivered Via Telerehabilitation in Children With Unilateral Cerebral Palsy: A Prospective Randomized Controlled Trial
Key facts
- Who runs it
- Istanbul University
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 42 people enrolled
- Started
- 12 Dec 2023
- Ended
- 25 Sept 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- mCIMT via Telerehabilitation
- home exercise program
- Record updated
- 19 November 2025
Who can take part
- Age
- 4 years to 12 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 19 criteriaShow less
Who can take part
- Inclusion between the ages of 4-12
- Diagnosis of unilateral CP by a specialist
- Ability to extend the suspected wrist more than 10°
- Demonstration of ability to follow simple commands and participation in assigned tasks
- Gross Motor Function Classification System Level 1 or 2
- Manual Skills Classification System Level 1, 2 or 3
- Muscle tone is normal/mild/moderate (Modified Ashworth Scale level 0-1-2)
- No contractures in the upper extremity
- Agrees to attend intensive therapy sessions and to stop all other upper extremity therapeutic interventions for the 3-month follow-up period
Who cannot take part
- Current or previous treatments not compatible with the study treatment protocol
- Orthopedic surgery (tendon transfer/tendon lengthening) performed on the affected upper extremity
- Cognitive impairment that causes inability to understand and perform simple commands and tasks
- Uncontrolled disease (endocrinologic, cardiovascular, pulmonary, hematologic, hepatic, renal), active systemic inflammatory disease, and/or history of malignancy
- Significant contractures in the wrist, elbow, and fingers that prevent daily activities
- Lack of active movement in the affected upper extremity
- Inability to continue treatment protocol due to school schedule
- Botulinum toxin injection into upper extremity muscles within the last 6 months
- Dorsal rhizotomy
- Intrathecal baclofen pump
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Aim:In this prospective and randomized controlled thesis study; we aimed to compare Modified Constraint-Induced Movement Therapy (mCIMT) delivered via Telerehabilitation with the home program in children with Unilateral Cerebral Palsy (CP) and to determine whether Telerehabilitation has a positive effect on upper extremity functions and quality of life.
Read full original descriptionShow less
Method: In our prospective and randomized controlled study, 42 children with unilateral cerebral palsy were included and randomized as the mCIMT group delivered via Telerehabilitation (n=21) and the control group (n=21).
The first group received mCIMT treatment together with Telerehabilitation for 1 hour, 3 times a week for 6 weeks. In addition, 30 minutes of indoor activity practices were performed every day.
The second group received a home program under the supervision of parents for 1 hour, 3 times a week for 6 weeks.
.In the randomized double-blind study, initial assessments, post-treatment and follow-up assessments were performed by the researcher who was blinded to the group distribution.
The primary outcome measure was the Assisting Hand Assessment (AHA), which was used to evaluate upper extremity function. The researcher administering this assessment was blinded to group allocation. Secondary outcome measures included the Modified Jebsen Taylor Hand Function Test, range of motion assessed with a goniometer, spasticity evaluated using the Modified Ashworth Scale, grip strength measured with a Jamar dynamometer, manual ability classified using the Manual Ability Classification System (MACS), activities of daily living assessed by ABILHAND-Kids, and quality of life evaluated using the KINDL questionnaire.
Post-treatment assessments were performed at the beginning of the study and 6 weeks after treatment.
The 2 groups in the trial
- via Telerehabilitation mCIMTExisting treatment, for comparison
The first group received mCIMT treatment together with Telerehabilitation for 1 hour, 3 times a week for 6 weeks. In addition, 30 minutes of indoor activity practices were performed every day. The second group received a home program under the supervision of parents for 1 hour, 3 times a week for 6 weeks.
Treatment: mCIMT via Telerehabilitation
- home exercises control groupExisting treatment, for comparison
A 1-hour home program will be implemented 3 days a week.
Treatment: home exercise program
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- In Our Prospective and Randomized Controlled Study, 42 Children With Unilateral Cerebral Palsy Were Included and Randomized as the mCIMT Group Delivered Via Telerehabilitation (n=21) and the Control Group (n=21). The First Group Received mCIMT Treatment Together With Telerehabilitation for 1 Hour, 3 Times a Week for 6 Weeks. In Addition, 30 Minutes of Indoor Activity Practices Were Performed Every Day. The Second Group Received a Home Program Under the Supervision of Parents for 1 Hour, 3 Times a Week for 6 Weeks.
- Record updated
- 19 November 2025