Dexmedetomidine added to desflurane anesthesia during keyhole colon surgery for colorectal tumors
Tests dexmedetomidine with desflurane anesthesia in adults having laparoscopic colon surgery.
Plain-language title generated from the registry record
Registry title: DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
Key facts
- Where
- Ho Chi Minh City, VietnamSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07239479, who can take part
Where in Vietnam
- Tam Anh TP. Ho Chi Minh General HospitalHo Chi Minh City, VietnamTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tam Anh Research Institute
- Trial code
- NCT07239479
- Record updated
- 30 December 2025
- Original description
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.Read full original descriptionShow less
Efficacy and Safety of Dexmedetomidine Combined With Desflurane in Laparoscopic Colectomy: A Randomized Double-Blind Controlled Clinical Trial (DEXDES Trial)
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.
Inclusion: Age 18-65 years; ASA Physical Status I-II; Elective laparoscopic colectomy; Written informed consent provided.
Exclusion: Chronic opioid or psychotropic medication use; Severe cardiac, hepatic, or renal disease; Atrioventricular block (grade II-III), sick sinus syndrome; Significant intraoperative bleeding or hemodynamic instability; COPD or bronchial asthma.