Two Catheter Ablation Methods for Fast Heart Rhythms After a Heart Attack
Compares two catheter ablation approaches for ventricular tachycardia in people with a prior heart attack.
Plain-language title generated from the registry record
Registry title: Endo-ePIcardial Versus Endocardial Only Catheter Ablation for ISchemic Driven Ventricular Tachycardia (EPISODE VT)
Key facts
- Where
- Bydgoszcz, Gdansk, Krakow, Poznan, Szczecin, and Warsaw, PolandSee the 9 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT07240441, who can take part
Where in Poland
- University Hospital No. 1 in BydgoszczBydgoszcz, PolandNot yet recruiting
- University Clinical Center based in GdańskGdansk, PolandNot yet recruiting
- Independent Public Health Care Facility University Hospital in KrakowKrakow, PolandNot yet recruiting
- University Clinical Hospital in PoznańPoznan, PolandNot yet recruiting
- University Clinical Hospital No. 2 PUM in SzczecinSzczecin, PolandNot yet recruiting
- Grochowski Hospital named after Dr. Rafał Masztak, MDWarsaw, PolandNot yet recruiting
- Medical University of WarsawWarsaw, PolandTaking people
- Medicover HospitalWarsaw, PolandTaking people
- National Institute of CardiologyWarsaw, PolandNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- MEDICOVER SP Z O.O.
- Trial code
- NCT07240441
- Record updated
- 20 November 2025
- Original description
The EPISODE VT trial is designed to compare efficacy and safety of two modalities for interventional treatment - endocardial ablation and endo-epicardial ablation in a population of patients with post myocardial infarction (ICD 10 - I25.2) ventricular tachycardias (ICD 10 - I47.2), who are protected by an implantable cardioverter-defibrilator (ICD) and meet study inclusion criteria.Read full original descriptionShow less
Endo-ePIcardial Versus Endocardial Only Catheter Ablation for ISchemic Driven Ventricular Tachycardia (EPISODE VT) - Multicenter, Prospective, Randomized Trial
The EPISODE VT trial is designed to compare efficacy and safety of two modalities for interventional treatment - endocardial ablation and endo-epicardial ablation in a population of patients with post myocardial infarction (ICD 10 - I25.2) ventricular tachycardias (ICD 10 - I47.2), who are protected by an implantable cardioverter-defibrilator (ICD) and meet study inclusion criteria.
Inclusion: Status after myocardial infarction (minimum 3 months before inclusion in the study); Documented post-infarction VT or VF; Implantable ICD (at least 2 weeks before ablation) or CRT-D (at least 2 months before ablation); A history of at least one from below:; One or more high energy interventions; Three or more adequate antitachycardia pacing therapies, including one symptomatic; Three or more episodes of VT in 24 hours (interrupted by ATP or shock) - electrical storm; Sustained VT recorded on ECG with a cycle length longer than the ICD detection threshold; Age between 18 and 85 years; Signed informed consent to participate in the study.
Exclusion: Previous heart surgery; Acute conditions that prevent ablation (including active infection, overt hyperthyroidism and others listed below); Active neoplastic disease; Heart failure with NYHA IV; Left ventricle ejection fraction < 20%; Renal failure (eGFR < 20 mL/min/1.73m2); Obesity with BMI > 40 kg/m2; Pregnancy or breastfeeding; Fresh ballot thrombus in the left ventricle; Suspicion of massive adhesions in the pericardium that may impede pericardial puncture; Ablation of the post-infarction VT in the left ventricle in medical history; Life expectancy less than 12 months.