Two Catheter Ablation Methods for Fast Heart Rhythms After a Heart Attack
Compares two catheter ablation approaches for ventricular tachycardia in people with a prior heart attack.
Plain-language title generated from the registry record
Registry title: Endo-ePIcardial Versus Endocardial Only Catheter Ablation for ISchemic Driven Ventricular Tachycardia (EPISODE VT)
Key facts
- Where
- Bydgoszcz, Gdansk, Krakow, Poznan, Szczecin, and Warsaw, PolandSee the 9 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who had a heart attack at least 3 months ago, have a heart rhythm problem called ventricular tachycardia, and have an implanted defibrillator (ICD or CRT-D).
- Age
- 18 to 85 years
- Sex
- All sexes can join.
- Disease stage
- Heart attack at least 3 months ago, with documented ventricular tachycardia or ventricular fibrillation after the heart attack. At least one of these in the past: a high energy shock, 3 or more pacing therapies from the device, 3 or more VT episodes in 24 hours, or a long VT recorded on ECG.
- Earlier treatment
- An ICD implanted at least 2 weeks before the ablation, or a CRT-D at least 2 months before. No earlier ablation of post-infarction VT in the left ventricle and no earlier heart surgery.
Main reasons for not taking part
- BMI above 40 kg/m2
- Left ventricle ejection fraction below 20%
- Pregnancy or breastfeeding
- Kidney failure (eGFR below 20 mL/min/1.73m2)
- Heart failure with NYHA IV, active cancer, or life expectancy under 12 months
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT07240441, who can take part
Where in Poland
- University Hospital No. 1 in BydgoszczBydgoszcz, PolandContact: Krupa WNot yet recruiting
- University Clinical Center based in GdańskGdansk, PolandContact: Królak TNot yet recruiting
- Independent Public Health Care Facility University Hospital in KrakowKrakow, PolandContact: Jastrzębski MNot yet recruiting
- University Clinical Hospital in PoznańPoznan, PolandContact: Derejko P Prof. Paweł Derejko, MD, PhDNot yet recruiting
- University Clinical Hospital No. 2 PUM in SzczecinSzczecin, PolandContact: Kiedrowicz R Radosław Kiedrowicz, MD, PhDNot yet recruiting
- Grochowski Hospital named after Dr. Rafał Masztak, MDWarsaw, PolandContact: Baran Dr. Jakub Baran, MD, PhDNot yet recruiting
- Medical University of WarsawWarsaw, PolandContact: Peller M Michał Peller, MD, PhDTaking people
- Medicover HospitalWarsaw, PolandContact: Klimowicz K Study coordinatorTaking people
- National Institute of CardiologyWarsaw, PolandContact: Maciąg A Aleksander Maciąg, MD, PhDNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- MEDICOVER SP Z O.O.
- Trial code
- NCT07240441
- Record updated
- 20 November 2025
- Original description
The EPISODE VT trial is designed to compare efficacy and safety of two modalities for interventional treatment - endocardial ablation and endo-epicardial ablation in a population of patients with post myocardial infarction (ICD 10 - I25.2) ventricular tachycardias (ICD 10 - I47.2), who are protected by an implantable cardioverter-defibrilator (ICD) and meet study inclusion criteria.Read full original descriptionShow less
Endo-ePIcardial Versus Endocardial Only Catheter Ablation for ISchemic Driven Ventricular Tachycardia (EPISODE VT) - Multicenter, Prospective, Randomized Trial
The EPISODE VT trial is designed to compare efficacy and safety of two modalities for interventional treatment - endocardial ablation and endo-epicardial ablation in a population of patients with post myocardial infarction (ICD 10 - I25.2) ventricular tachycardias (ICD 10 - I47.2), who are protected by an implantable cardioverter-defibrilator (ICD) and meet study inclusion criteria.
Inclusion: Status after myocardial infarction (minimum 3 months before inclusion in the study); Documented post-infarction VT or VF; Implantable ICD (at least 2 weeks before ablation) or CRT-D (at least 2 months before ablation); A history of at least one from below:; One or more high energy interventions; Three or more adequate antitachycardia pacing therapies, including one symptomatic; Three or more episodes of VT in 24 hours (interrupted by ATP or shock) - electrical storm; Sustained VT recorded on ECG with a cycle length longer than the ICD detection threshold; Age between 18 and 85 years; Signed informed consent to participate in the study.
Exclusion: Previous heart surgery; Acute conditions that prevent ablation (including active infection, overt hyperthyroidism and others listed below); Active neoplastic disease; Heart failure with NYHA IV; Left ventricle ejection fraction < 20%; Renal failure (eGFR < 20 mL/min/1.73m2); Obesity with BMI > 40 kg/m2; Pregnancy or breastfeeding; Fresh ballot thrombus in the left ventricle; Suspicion of massive adhesions in the pericardium that may impede pericardial puncture; Ablation of the post-infarction VT in the left ventricle in medical history; Life expectancy less than 12 months.