Orforglipron and Heart Events in People With Heart Artery Disease or Chronic Kidney Disease
Tests orforglipron against placebo for heart problems in adults with artery or kidney disease.
Plain-language title generated from the registry record
Registry title: A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Key facts
- Where
- Adana, Afyonkarahisar, Ankara, Antalya, Çanakkale, Çorum, Eskişehir, Istanbul, Kayseri, Kocaeli, Küçükçekmece, Malatya, Meram, and Sakarya, TürkiyeSee the 14 sites
- Phase
- Phase 3
Where in Türkiye
- Adana Sehir Egitim ve Arastirma HastanesiAdana, TürkiyeTaking people
- Afyon Kocatepe Üniversitesi Tıp FakültesiAfyonkarahisar, TürkiyeTaking people
- Ankara Etlik City HospitalAnkara, TürkiyeTaking people
- Akdeniz Universitesi HastanesiAntalya, TürkiyeTaking people
- Çanakkale Onsekiz Mart ÜniversitesiÇanakkale, TürkiyeTaking people
- Hitit Universitesi Corum Erol Olcok Egitim Ve Arastirma HastanesiÇorum, TürkiyeNot yet recruiting
- Eskisehir Osmangazi UniversityEskişehir, TürkiyeTaking people
- Mehmet Akif Ersoy Research and Training HospitalIstanbul, TürkiyeTaking people
- Erciyes Universitesi Tıp Fakultesi HastaneleriKayseri, TürkiyeTaking people
- Kocaeli ÜniversitesiKocaeli, TürkiyeTaking people
- Istanbul Kanuni Sultan Suleyman Egitim ve Arastirma HastanesiKüçükçekmece, TürkiyeTaking people
- Inonu Universitesi Turgut Ozal Tıp MerkeziMalatya, TürkiyeTaking people
- Necmettin Erbakan University Meram Medical FacultyMeram, TürkiyeTaking people
- Sakarya Training and Research HospitalSakarya, TürkiyeTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Eli Lilly and Company
- Trial code
- NCT07241390EU 2025-523123-22-00
- Record updated
- 4 November 2026
- Original description
The purpose of this study is to measure cardiovascular outcomes with orforglipron compared with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Participation in the study will last about 5 years.Read full original descriptionShow less
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Event-Driven Study to Investigate the Effect of Orforglipron on the Incidence of Major Adverse Cardiovascular Events in Participants With Established Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease
The purpose of this study is to measure cardiovascular outcomes with orforglipron compared with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Participation in the study will last about 5 years.
Inclusion: Have established ASCVD and/or CKD.
Exclusion: Have had a major heart condition within 60 days prior to screening; Have type 1 diabetes; Have New York Heart Association Functional Classification Class IV heart failure.