Ejaculation or Abstinence Before Prostate Cancer Surgery and Seminal Vesicle Size
Compares recent ejaculation with abstinence before prostate removal surgery in men with prostate cancer.
Plain-language title generated from the registry record
Registry title: Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy
Key facts
- Where
- Taipei, TaiwanSee the site
Where in Taiwan
- National Taiwan University Cancer CenterTaipei, TaiwanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT07243795
- Record updated
- 3 December 2025
- Original description
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are:Read full original descriptionShow less
Impact of Preoperative Ejaculation or Abstinence on Seminal Vesicle Size and Intraoperative Dissection Parameters During Radical Prostatectomy: A Randomized Controlled Trial
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are:
Does ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more?
Does seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy?
Researchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them.
Participants will:
Follow specific instructions to either ejaculate or abstain before surgery
Undergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery
Have their surgical dissection time and difficulty rated by the operating surgeon
Inclusion: Male patients aged 18 years or older; Histologically confirmed prostate cancer; Scheduled for radical prostatectomy; Able and willing to comply with assigned ejaculation or abstinence protocol; Willing to complete preoperative questionnaire; Willing to undergo transrectal ultrasound (TRUS) 12-14 hours before surgery; Able to understand and sign informed consent.
Exclusion: Prior bilateral seminal vesicle resection or congenital absence of seminal vesicles; Hormone therapy within 6 months before surgery; Prior prostate cancer treatment; Severe anorectal disease or history of anorectal surgery preventing TRUS; Cognitive or psychiatric conditions impairing informed consent; Anatomical abnormalities preventing SV identification; Inability to recall ejaculation history in the past 3 days; Inability to follow behavioral instructions or TRUS protocol; Incomplete data or poor-quality imaging; Belonging to a vulnerable population (e.g., minors, prisoners, pregnant individuals, cognitively impaired, etc.).