Long-term follow-up of adults with metabolic syndrome and prediabetes
Follows adults with metabolic syndrome and prediabetes to see how health changes over time.
Plain-language title generated from the registry record
Registry title: Metabolic Syndrome and Prediabetes
Key facts
- Where
- Taipei, TaiwanSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults diagnosed with metabolic syndrome or prediabetes. They will be followed over time to track risk factors, disease progression, nutrition and physical function.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- A doctor's diagnosis of metabolic syndrome (at least 3 of 5 criteria: waist size or BMI, fasting blood sugar, blood pressure, triglycerides, HDL cholesterol) or prediabetes (HbA1c between 5.7% (39 mmol/mol) and 6.4% (46 mmol/mol))
- Biomarker or test result
- Waist circumference ≥ 90 cm (35 in) in men or ≥ 80 cm (31 in) in women, or BMI ≥ 27 kg/m². Fasting plasma glucose ≥ 100 mg/dL (5.6 mmol/L). Blood pressure: systolic ≥ 130 mmHg or diastolic ≥ 85 mmHg. Triglycerides ≥ 150 mg/dL (1.7 mmol/L). HDL-C < 40 mg/dL (1 mmol/L) in men or < 50 mg/dL (1.3 mmol/L) in women. HbA1c between 5.7% (39 mmol/mol) and 6.4% (46 mmol/mol) for prediabetes.
Main reasons for not taking part
- People who cannot understand the study information or procedures
- People who cannot follow the required assessments or study protocols
- Any other condition that the principal investigator judges makes taking part unsuitable
- People who cannot complete basic physical examinations and assessments
- People who have not signed written informed consent
Read by machine on 12 November 2026.
Where in Taiwan
- National Taiwan University HospitalTaipei, TaiwanContact: Chia-Wen Lu, Present ProfessorTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT07243821
- Record updated
- 17 September 2026
- Original description
This study aims to establish a cohort of individuals with metabolic syndrome and prediabetes to enable long-term follow-up of risk factors, disease progression, and the development of obesity-related complications. The study will also monitor changes in nutritional status and physical function over time, in order to identify key prognostic determinants influencing clinical outcomes.Read full original descriptionShow less
Cohort Studies on Metabolic Syndrome and Prediabetes
This study aims to establish a cohort of individuals with metabolic syndrome and prediabetes to enable long-term follow-up of risk factors, disease progression, and the development of obesity-related complications. The study will also monitor changes in nutritional status and physical function over time, in order to identify key prognostic determinants influencing clinical outcomes.
Metabolic syndrome and prediabetes are chronic multisystem disorders, and poor long-term control is closely associated with the development of various complications. Moreover, malnutrition and functional decline are common comorbid conditions that further impair quality of life and impose a substantial burden on healthcare resources.
Inclusion: Adults aged 18 years or older; Individuals clinically diagnosed by a physician as having metabolic syndrome (meeting at least three of the following five criteria) or prediabetes:; (A) Waist circumference: ≥ 90 cm in men or ≥ 80 cm in women, or body mass index (BMI) ≥ 27 kg/m²; (B) Fasting plasma glucose (AC): ≥ 100 mg/dL. (C) Blood pressure: Systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 85 mmHg; (D) Triglycerides (TG): ≥ 150 mg/dL. (E) High-density lipoprotein cholesterol (HDL-C): < 40 mg/dL in men or < 50 mg/dL in women; Individuals meeting the definition of prediabetes, defined as glycated hemoglobin (HbA1c) between 5.7% and 6.4%; Participants who are willing to participate in the study and have signed written informed consent; Participants who are able to complete basic physical examinations and assessment procedures.
Exclusion: Any other condition that, in the clinical judgment of the principal investigator, deems the individual unsuitable for participation; Individuals unable to comprehend the study information or procedures; Individuals unable to comply with the required assessments or study protocols.