NCT07247240Not yet recruitingPhase 4
Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia
Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia With Early Pulmonary Hypertension
Source: ClinicalTrials.gov · Last updated 25 Nov 2025
Brief summary (registry, in English)
This multicenter, prospective, single-arm study aims to evaluate the efficacy of inhaled nitric oxide (iNO) in neonates with congenital diaphragmatic hernia (CDH) and early pulmonary hypertension. Short-term treatment response will be assessed by the changes in oxygenation index and other parameters including echocardiographic parameters at predefined intervals.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 30 Sept 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Asan Medical Center
- NCT number
- NCT07247240
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 40
- From 1 Nov 2025 to the primary completion date, 31 Dec 2028
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous treatment of pulmonary vasodilators including inhaled nitric oxide
Other illness
- Combined congenital heart disease requiring neonatal intervention or surgery
Other
- on ECMO treatment
Who the study is looking for
- Bochdalek type congenital diaphragmatic hernia
- Gestational age at 34 weeks or more and within 14 days after birth
- Hypoxic respiratory failure and pulmonary hypertension
Age in the registry: 1 Minute to 14 days · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chonnam National University Hospital Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
| Asan Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Seoul National University Children's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Severance hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.