How Generalized Myasthenia Gravis Is Treated in Everyday Care in Russia
Observes treatments and outcomes in adults with AChR antibody-positive generalized myasthenia gravis.
Key facts
- Who runs it
- AstraZeneca
- Where
- Kazan', Moscow, Novosibirsk, Rostov-on-Don, Saint Petersburg, Samara, and Ufa, RussiaSee the 7 sites
- Trial code
- Registry title
- Epidemiological Study of Treatment Approaches in AChR-Antibody Positive Generalized Myasthenia Gravis in Russia
- Status
- Recruiting
- People taking part
- 450 people, planned
- Started
- 23 Dec 2025
- Expected to end
- 31 Dec 2029
- Type of study
- Observational
- Record updated
- 14 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The study is looking for adults with generalized myasthenia gravis who test positive for acetylcholine receptor (AChR) antibodies. It observes how they are treated in routine care in Russia.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Generalized myasthenia gravis (gMG). Ocular-only myasthenia gravis is not included.
- Biomarker or test result
- Positive for acetylcholine receptor (AChR) antibodies
Main reasons for not taking part
- Currently taking part in a clinical study of gMG treatment
- Ocular myasthenia gravis only
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Adults (≥18 years) diagnosed with generalized MG positive for acetylcholine receptor (AChR) antibodies
- Provision of signed and dated written informed consent
Who cannot take part
- Participants currently enrolled in clinical studies for treatment of gMG
- Ocular MG only
Where in Russia
- Kazan'Hospital not named in the registryTaking people
- MoscowHospital not named in the registryTaking people
- NovosibirskHospital not named in the registryTaking people
- Rostov-on-DonHospital not named in the registryTaking people
- Saint PetersburgHospital not named in the registryTaking people
- SamaraHospital not named in the registryTaking people
- UfaHospital not named in the registryTaking people
About the trial
What the trial wants to find out
This is a multicenter, non-interventional, retrospective-prospective, single-arm observational study designed to describe real-world treatment approaches and clinical outcomes among adults with acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (gMG) in routine clinical practice in Russia.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Multicenter Non Interventional Single Arm Retrospective-prospective Observational Study in Therapeutic Approaches in AChR-Antibody Positive Generalized Myasthenia Gravis (gMG) in Real Clinical Practice in Russia
- Plain-language title
- How Generalized Myasthenia Gravis Is Treated in Everyday Care in RussiaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 14 October 2026