Type 2 Diabetes and Associated Factors in Mexico
Key facts
- Where
- Mexico City, MexicoSee the 3 sites
Where in Mexico
- Coordinación de Investigación en SaludMexico City, MexicoNo longer taking part
- División de Investigación en SaludMexico City, MexicoNo longer taking part
- Instituto Mexicano del Seguro SocialMexico City, MexicoNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Coordinación de Investigación en Salud, Mexico
- Trial code
- NCT07248891
- Record updated
- 4 December 2025
- Original description
The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in adult patients in Mexico.Read full original descriptionShow less
Comprehensive Study of Associated Factors With Type 2 Diabetes in Mexico: Protocol
The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in adult patients in Mexico.
The main questions it aims to answer are:
Which molecular and clinical factors are associated with poor glycemic control (HbA1c > 7%)?
Which factors are linked to the presence of diabetic nephropathy (GFR < 60 mL/min/1.73 m²)?
Participants:
Provide informed consent and clinical history.
Undergo a clinical and physical evaluation (including six-minute walk test).
Complete lifestyle, dietary, and therapeutic adherence questionnaires.
Provide blood samples for biochemical, inflammatory, and transcriptomic (RNA-Seq) analysis.
Researchers integrate clinical, biochemical, and transcriptomic data using statistical modeling to identify a characteristic molecular fingerprint of poor metabolic control and diabetes-related complications.
Inclusion: Adults 18 years of age or older; Established diagnosis of Type 2 Diabetes Mellitus (T2D); Patients receiving care at Family Medicine Units in Coahuila, Jalisco, or Veracruz; Willingness to voluntarily participate in the study; Ability to understand the study procedures and provide written informed consent.
Exclusion: Current use of steroids; Concomitant illness with inflammatory or autoimmune component (rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, psoriatic arthritis, gout); History of cerebrovascular disease, heart failure or kidney failure that required hospitalization in the previous month; History of infection in the previous 10 days (respiratory tract infection, gastroenteritis, urinary tract infection, soft tissue infection); Severe obesity with BMI > 40 kg/m2. History of bariatric surgery; Pregnant or lactating mother; Tobacco use (in the last 3 months).