Outdoor Work, Sun Exposure and Skin Melanoma in Modena, Italy
Studies whether working in the sun is linked to melanoma in adults.
Key facts
- Who runs it
- University of Modena and Reggio Emilia
- Where
- Modena, ItalySee the site
- Trial code
- Registry title
- Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
- Status
- Recruiting
- People taking part
- 300 people, planned
- Started
- 7 Jul 2025
- Expected to end
- Nov 2027
- Type of study
- Observational, 2 groups
- Record updated
- 18 December 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adult patients of the Modena University Hospital Dermatology Clinic who are being checked for a suspected skin lesion. It studies the link between work in the sun and melanoma.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- A suspected skin lesion that has been examined at the clinic. People with melanoma and people without melanoma are both studied.
Main reasons for not taking part
- Under 18 years of age
- Cognitive impairment that prevents reliable answers to the interview or recalling past exposures
- Cannot understand and sign the consent form in Italian
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Be a patient of the Dermatology Clinic at the University Hospital of Modena
- Be 18 years of age or older
- Have undergone a dermatological screening for a suspected skin lesion
- Be able to understand and sign an informed consent form in italian language
Who cannot take part
- Have cognitive impairment that prevents providing reliable answers to the interview or recalling past exposures
- Be under 18 years of age
Where in Italy
- Dipartimento di Scienze Biomediche, Metaboliche e NeuroscienzeModena, ItalyContact: Alberto Modenese, MD, PhDTaking people
About the trial
What the trial wants to find out
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
Read full original descriptionShow less
The main questions it aims to answer are:
* Is there a connection between working outdoors and developing types of melanoma that are linked to long-term sun exposure? * Can we use recent criteria from the Italian workers' compensation authority (Istituto Nazionale per l'Assicurazione contro gli Infortuni sul Lavoro, INAIL) to better identify and report these melanomas as occupational diseases?
Participants in this study will:
* Be patients of the Modena University Hospital Dermatology Clinic who are already undergoing a skin biopsy for a suspected lesion. * Take part in a one-time interview with a trained healthcare worker.
Answer questions about their:
* Job history and specific work locations (to calculate local UVR exposure). * Sun exposure habits at work and in their free/holiday time. * Use of sun protection (e.g., sunscreen, protective clothing). * Use of tanning beds. * Natural skin color and tendency to sunburn (and other elements to determine their specific skin phototype). * Other personal and family health factors.
Researchers will compare two groups:
* Cases: 120 participants who are diagnosed with melanoma after the biopsy. * Controls: 180 participants who screened negative for melanoma but may show another skin condition.
By comparing these groups, researchers aim at better understanding the role of outdoor work as a risk factor for specific melanoma subtypes. For participants diagnosed with a melanoma that is likely linked to their job, the study team will promote its reporting as an occupational disease.
The 2 groups in the trial
- Cases
Participants in this group are patients recruited from the Dermatology Clinic who have received a new, histopathologically confirmed diagnosis of skin melanoma.
- Controls
Participants in this group are patients recruited from the same Dermatology Clinic who have been screened negative for melanoma. These controls are matched to the cases based on similar age and gender.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
- Plain-language title
- Outdoor Work, Sun Exposure and Skin Melanoma in Modena, ItalyGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 18 December 2025