Pilot Study of StudyU for N-of-1 Trials in HFrEF Patients (N-of-1 App)
Key facts
- Where
- New York, United StatesSee the site
- Phase
- Phase 4
Where in United States
- Weill Cornell Medical CollegeNew York, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Weill Medical College of Cornell University
- Trial code
- NCT07252310
- Record updated
- 19 February 2026
- Original description
This study will look at whether using a phone app called StudyU can help people with Heart Failure with Reduced Ejection Fraction (HFrEF) reach their recommended dose on their beta blocker.Read full original descriptionShow less
Pilot Study of Acceptability and Feasibility of StudyU for N-of-1 Trials
This study will look at whether using a phone app called StudyU can help people with Heart Failure with Reduced Ejection Fraction (HFrEF) reach their recommended dose on their beta blocker.
Inclusion: Adults ≥ 65 years old; A history of HFrEF per electronic medical record review/clinician impression that is defined as an EF <50% that is shown from any imaging modality; Taking less than the maximal dose of beta blocker per physician recommendation at time of enrollment; Access to a smartphone or device that can perform many of the same functions as a computer, typically having a touchscreen interface, internet access, and an operating system capable of running downloaded applications.
Exclusion: Clinical instability (this N-of-trial is appropriate for stable conditions only); Decompensated HF; Hospitalized in the past 30 days; Medication changes or procedures in prior 14 days (to prevent confounding from other interventions) at PI discretion; Moderate-severe dementia or psychiatric disorder precluding informed consent; History of noncompliance or inability to complete study procedures; Any condition that, in Principal Investigator or treating physician's opinion, makes the patient unsuitable for study participation; Do not have access to a smartphone or tablet; Estimated life expectancy <6 months; Language barrier that will preclude informed consent and ability to comprehend study procedures; Enrollment in a clinical trial not approved for co-enrollment.