NCT07253038Recruiting
Evaluation of Three Tests to Assess Social Cognition in Huntington Disease
The Social-HD Study: A Cross-Sectional Observational Study of Social Cognition in Early Huntington Disease
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease. Huntington disease affects motor function, psychological well-being and cognitive functions ("thinking abilities" such as paying attention, remembering and solving problems). It is also believed to affect important social functions, including the ability to understand others' intentions and emotions (social cognition). The test of interest in this study is called The Double Movie for the Assessment of Social Cognition-Multiple Choice (DMASC-MC) and will be compared to two other similar and well-known tests. The main question which the study aims to answer is: • Is DMASC-MC a useful tool for detecting problems with social functioning in adult persons with early Huntington disease? In the study, participants will meet with a medical doctor and a psychologist for assessment of different symptoms related to Huntington disease, including social functioning. Better methods for identifying problems with social functioning could help persons with Huntington disease and their families in mainly two ways. Firstly, it could increase their understanding of how the disease has affected them. Secondly, a better understanding of these problems could lead to better recommendations and interventions from medical teams, which would also benefit persons with Huntington disease and families.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 Sept 2027
- Lead sponsor
- Region Skane
- Diseases
- Huntington's disease
- NCT number
- NCT07253038
What you commit to
- Study type: Observational
- Planned participants: 40
- From 1 Dec 2025 to the primary completion date, 1 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ongoing alcohol/drug addiction
Other illness
- Dementia or MOCA\<19, The Mini Mental State Examination (MMSE) \<19
- Other neurological disorders
Other
- Participants in both groups are excluded from the study if any of the following criteria apply:
- Ongoing psychosis
- Other native language than Swedish
- Severe problems with vision and hearing
Who the study is looking for
- Clinical diagnosis of HD
- CAG repeat: 40 and more
- 1\. No heritage of HD or negative pre-symptomatic HD gene test
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Skåne University Hospital, Region Skåne Coordinator of this site? Confirm its status | Lund | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.