How Rehabilitation Intensity Affects Recovery in Adults After Stroke Linked to Atrial Fibrillation
Follows adults in stroke rehabilitation, including atrial fibrillation-related stroke, to compare recovery.
Plain-language title generated from the registry record
Registry title: Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study
Key facts
- Where
- Barcelona, SpainSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who had their first-ever ischemic stroke in the brain and need inpatient rehabilitation.
- Age
- 18 to 99 years
- Sex
- All sexes can join.
- Disease stage
- First-ever ischemic stroke in the brain (intracerebral).
Main reasons for not taking part
- Bleeding inside the skull (intracranial haemorrhage)
- Bleeding that developed inside the stroke area (symptomatic hemorrhagic transformation)
- New strokes (infarcts) after the first stroke
- Other neurological or psychiatric conditions
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Source: NCT07253974, who can take part
Where in Spain
- Rehabilitation Research Group, IMIMBarcelona, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Parc de Salut Mar
- Trial code
- NCT07253974
- Record updated
- 15 December 2025
- Original description
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation. The main questions it aims to answer are:Read full original descriptionShow less
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study. TARGET: Health Virtual Twins for the Personalised Management of Stroke Related to Atrial Fibrillation".
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation. The main questions it aims to answer are:
Do patients with stroke of Atrial-related subtypes (AFRS) have distinct rehabilitation needs and functional outcomes compared to non-AFRS patients? Does higher-intensity inpatient rehabilitation (3-5 sessions/day) result in better functional recovery at six months (measured by the Barthel Index) than moderate-intensity programs (1 session/day)? The study is non-invasive, does not interfere with usual care. The investigators' ultimate goal is to enhance the understanding of recovery after following different rehabilitation usual programs.
Inclusion: -.
Exclusion: intracranial haemorrhage, symptomatic hemorrhagic transformation, new infarcts after the initial stroke or other neurological or psychiatric conditions.