Frontlight ResearchEarly access
Enrolling by invitationNo phase
Long-term follow-up of people given the gene-editing treatment PBGENE-HBV for chronic hepatitis B
Follows people with chronic HBV infection who earlier received PBGENE-HBV.
Key facts
- Who runs it
- Precision BioSciences, Inc.
- Where
- Hong Kong, Hong KongSee the siteAlso in 3 other countries, 3 sites
- Trial code
- Registry title
- A Long-term Observational Study in Participants Who Have Received PBGENE-HBV
- Status
- Enrolling by invitation
- People taking part
- 45 people, planned
- Started
- 25 Dec 2025
- Expected to end
- Jun 2040
- Type of study
- Observational
- Treatments tested
- PBGENE-HBV
- Record updated
- 22 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people who already received at least 1 dose of PBGENE-HBV in an earlier clinical study. This is a long-term follow-up study.
- Age
- 19 Years to 80 Years
- Sex
- All sexes can join.
- Earlier treatment
- Must have received at least 1 dose of PBGENE-HBV in a prior clinical study.
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- Participant has received at least 1 dose of PBGENE-HBV investigational product in a prior clinical study
- Participant, or their legally authorized representative, has provided signed informed consent
Who cannot take part
- N/A
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 19 and 80 years old?
Where in Hong Kong
Also in 3 other countries, 3 sites
- Queen Mary Hospital University of Hong KongHong Kong, Hong KongEnrolling by invitation
About the trial
What the trial wants to find out
Participants who received at least one dose of PBGENE-HBV will be enrolled in this LTFU study.
Treatments tested
- PBGENE-HBV
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Long-term Observational Study in Participants Who Have Received PBGENE-HBV, an In Vivo Gene Editing Investigational Product, in a Prior Clinical Study
- Plain-language title
- Long-term follow-up of people given the gene-editing treatment PBGENE-HBV for chronic hepatitis BGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07254208, who can take part
- Record updated
- 22 April 2026