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Studying Iron-Linked Cell Death in Systemic Lupus Erythematosus

Studies blood samples from people with lupus to explore iron-driven cell death.

Plain-language title generated from the registry record
Registry title: Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus

Key facts

Where
Bordeaux, FranceSee the site

Where in France

  • CHU de Bordeaux - service de rhumatologieBordeaux, FranceTaking people

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Trial details

Who runs it
University Hospital, Bordeaux
Trial code
NCT07260942
Record updated
18 May 2026
Original description
The study aims at defining the role of ferroptosis s in the physiopathology of systemic lupus erythematosus (SLE). Ferroptosis (phenomenon of cellular death regulated by iron) is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.Read full original descriptionShow less

Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus

The study aims at defining the role of ferroptosis s in the physiopathology of systemic lupus erythematosus (SLE). Ferroptosis (phenomenon of cellular death regulated by iron) is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.

Inclusion: age ≥ 18 years; diagnosis of systemic lupus erythematosus; being affiliated to health insurance, willing to participate and to sign informed consent; control group : patients with a diagnosis of rheumatoid arthritis or an inflammatory bowel disease.

Exclusion: patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent); pregnant or breastfeeding women.

ClinicalTrials.gov NCT07260942