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Heart Ultrasound Measure Predicting Early Problems After Heart Attack Treatment

Checks whether a heart ultrasound measure predicts early complications in people with heart attacks.

Plain-language title generated from the registry record
Registry title: LA Strain in Predicting Early Complication in STEMI After PPCI

Key facts

Where
Asyut, EgyptSee the site

Where in Egypt

  • Assiut UniversityAsyut, EgyptNo longer taking part

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Trial details

Who runs it
Assiut University
Trial code
NCT07263282
Record updated
12 December 2025
Original description
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI. The main questions it aims to answer are:Read full original descriptionShow less

Left Atrium Strain as a Predictor of In-Hospital Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI. The main questions it aims to answer are:

Is low parameters of left atrial strain associated early complication ? What is the correlation between LA strain parameters and conventional echocardiographic indices of left ventricular systolic and diastolic function ? Is there more affection to LA strain in certain territory over the others ? What is the correlation between LA strain and LA volume index across infarct territories ? Does LA strain Correlate with TAPSE and PASP to evaluate right-heart interactions ?

Inclusion: Adults aged ≥18 years; Diagnosed with ST-segment elevation myocardial infarction (STEMI) according to current ESC/AHA criteria; Underwent successful primary percutaneous coronary intervention (PPCI) within 12 hours of symptom onset; Sinus rhythm on admission ; Trans thoracic echocardiography (TTE) performed within 48 hours of admission with adequate image quality for speckle-tracking analysis.

Exclusion: Previous myocardial infarction or prior PCI/CABG; Prior cardiac surgery or known structural lesions that preventing reliable LA measurement; Patients known to have atrial fibrillation or other sustained supraventricular arrhythmias; Significant valvular heart disease (severe stenosis or regurgitation); Congenital heart disease or cardiomyopathy (hypertrophic, dilated, restrictive); Poor echocardiographic window preventing LA strain analysis ; Mechanical complications (e.g., papillary muscle rupture, VSD, free wall rupture); patient presenting with killip class III or IV from the start.

ClinicalTrials.gov NCT07263282