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NCT07263464Completed

The Association Between TNFSF4 Polymorphism and CD

The Association Between Tumor Necrosis Factor Superfamily Member 4 Polymorphism and Crohn's Disease

Source: ClinicalTrials.gov · Last updated 4 Dec 2025

Brief summary (registry, in English)

The goal of this observational study is to investigate the associations between tumor necrosis factor superfamily member 4 (TNFSF4) gene polymorphisms and the risk of Crohn's disease (CD), and to elucidate the impact of TNFSF4 gene variations on the CD clinical phenotype and the efficacy of ustekinumab (UST). The main question it aims to answer is: Does TNFSF4 polymorphism affect susceptibility to CD and the efficacy of UST in CD patients? Participants will have their blood drawn upon enrollment

Status (registry)
Completed
Study type
Observational
Enrollment
818 (actual)
First submitted
24 Nov 2025
Start date
1 Jan 2018
Primary completion date
31 May 2025
Lead sponsor
Second Affiliated Hospital of Wenzhou Medical University
NCT number
NCT07263464

What you commit to

  • Study type: Observational
  • Participants enrolled: 818
  • From 1 Jan 2018 to the primary completion date, 31 May 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • rheumatoid arthritis, systemic lupus erythematosus, intestinal tuberculosis, ischemic enteritis, radiation enteritis, tumors, etc.

Who the study is looking for

  • diagnosed CD based on comprehensive clinical, colonoscopy, histopathological, laboratory, and radiographic examination results

Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Second Affiliated Hospital of Wenzhou Medical University
Coordinator of this site? Confirm its status
WenzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.