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Two muscle facilitation approaches for arm function after a recent stroke

Compares two muscle exercise approaches for arm function in people after a recent stroke.

Plain-language title generated from the registry record
Registry title: Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Acute Stroke

Key facts

Where
Cairo, EgyptSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 50 and 60 years old?

Source: NCT07273201, who can take part

Where in Egypt

  • faculty of Physical Therapy, Cairo University, and El kasr El-Einy hospitalsCairo, EgyptTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Cairo University
Trial code
NCT07273201
Record updated
9 December 2025
Original description
This study is a randomized controlled clinical trial that will be carried out to investigate the effect of isolated versus synergetic muscle facilitation on upper limb functional performance in patients with acute stroke.Read full original descriptionShow less

Effect of Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Patients With Acute Stroke

This study is a randomized controlled clinical trial that will be carried out to investigate the effect of isolated versus synergetic muscle facilitation on upper limb functional performance in patients with acute stroke.

RESEARCH QUESTION:

Is there a difference between isolated and synergetic muscle facilitation on upper limb functional performance in patients with acute stroke?

It will be hypothesized that:

There will be no difference between isolated and synergetic muscle facilitation on upper limb task-oriented training in patients with acute stroke.

Treatment procedures:

Study group (A): patients will receive a physical therapy program in the form of a range of motion exercise, electrical muscle stimulation, stretching exercise, mental practice with motor imagery, and isolated muscle facilitation using electromyography (EMG) biofeedback for six weeks and followed by task-oriented training of the upper limb for six weeks control group (B): will receive a standard physical therapy program including range of motion exercise, electrical muscle stimulation, Mental practice with motor imagery and stretching exercise, synergetic muscle facilitation for six weeks, and followed by task-oriented training of the upper limb for six weeks.

Inclusion: Unilateral Middle cerebral artery (MCA) stroke patients; Brunnstrom stage of recovery 1\& 2; Normal body mass index (18.5 - 24.99 kg/m2); Dominant handedness.

Exclusion: Recurrent stroke; Perceptual, apraxia, major cognitive deficits; Subjects with cerebellar lesions, painful or subluxated shoulder, any contracture or deformity of the upper extremity.

ClinicalTrials.gov NCT07273201