Clinical Characteristics and Molecular Mechanism of Patients With Obstructive Sleep Apnea
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- How often do I need to come in, and for how long each time?
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Contact the study team: see the registry record → Contacts and Locations
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- Who runs it
- Capital Medical University
- Trial code
- NCT07277608
- Record updated
- 11 December 2025
- Original description
To clarify the clinical features of patients with obstructive sleep apnea; To construct a multi-omics database of patients with obstructive sleep apnea, and compare the effects of different degrees of sleep apnea on prognosis, immunity, and metabolism. The medium and long-term prognosis, complications, comorbidities, risk factors, and immune and metabolic dynamics of patients with sleep apnea after treatment were studied. To elucidate the biomarkers and therapeutic targets associated with obstructive sleep apnea.Read full original descriptionShow less
To clarify the clinical features of patients with obstructive sleep apnea; To construct a multi-omics database of patients with obstructive sleep apnea, and compare the effects of different degrees of sleep apnea on prognosis, immunity, and metabolism. The medium and long-term prognosis, complications, comorbidities, risk factors, and immune and metabolic dynamics of patients with sleep apnea after treatment were studied. To elucidate the biomarkers and therapeutic targets associated with obstructive sleep apnea.
Inclusion: Patients with suspected obstructive sleep apnea (OSA) admitted to the sleep center of the respiratory Department of Beijing Chaoyang Hospital, Capital Medical University; Volunteer to participate in the study and sign an informed consent, and can complete at least 1 year of follow-up.
Exclusion: Patients with obstructive sleep apnea who have been treated with impermanent positive pressure ventilation; Patients with severe respiratory failure requiring mechanical ventilation; Patients with severe heart, lung, liver, kidney, and central nervous system damage; Pregnant or lactating women; Refuse to participate in follow-up visits and/or take biological samples.