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Studying a laser treatment for eye pressure in pigmentary glaucoma

Observes eye pressure after a laser treatment in people with pigmentary glaucoma.

Plain-language title generated from the registry record
Registry title: IOP Reduction in Pigmentary Glaucoma Using DSLT

Key facts

Where
Houston, United StatesSee the site

Where in United States

  • Mann Eye InstituteHouston, United StatesTaking people

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Trial details

Who runs it
Mann Eye Institute
Trial code
NCT07281391
Record updated
9 April 2026
Original description
This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively. Clinical evaluations will include IOP and number of glaucoma medications.Read full original descriptionShow less

Direct Selective Laser Trabeculoplasty Providing Effective Intraocular Pressure Reduction in Pigmentary Glaucoma Patients

This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively. Clinical evaluations will include IOP and number of glaucoma medications.

Inclusion: Adult patients with pigmentary dispersion syndrome with elevated IOP or mild to moderate (based on AAO Preferred Practice Program criteria) pigmentary glaucoma with glaucomatous optic neuropathy and corresponding visual field/RNFL loss; Treatment naive, or washed out IOP ranging from ≥18-34 mmHg; Central corneal thickness (CCT) 480-600 µm; Able to complete medication washout and follow-up.

Exclusion: Prior incisional glaucoma surgery or glaucoma-related procedures in the study eye; Prior laser trabeculoplasty <3 years; Prior intraocular surgery and refractive surgery, except for cataract surgery unless greater than 2 years; Patients anticipating cataract surgery within the follow-up period; History of ocular inflammation and infection; All other secondary glaucoma including exfoliative; Patients unable to have DSLT treatment.

ClinicalTrials.gov NCT07281391