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How Diet and Gut Movement Relate to Symptoms in Children With Irritable Bowel Syndrome

Studies how food and gut movement relate to symptoms in children with irritable bowel syndrome.

Key facts

Who runs it
Children's Hospital of Philadelphia
Where
Philadelphia, United StatesSee the site
Trial code
Registry title
Diet and Motility in IBS
Status
Recruiting
People taking part
90 people, planned
Started
31 Jul 2023
Expected to end
Jun 2027
Type of study
Observational, 2 groups
Treatments tested
  • Wireless Patch System
Record updated
15 December 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children aged 8 to 18 with irritable bowel syndrome (IBS), and children without IBS as a comparison group. It studies diet, gut movement, and gut bacteria.

Age
8 to 18 years
Sex
Males and females
Disease stage
Children with IBS need a diagnosis of IBS (Rome IV criteria). Comparison children must have no diagnosis of an abdominal pain disorder.
Earlier treatment
No antibiotics in the past 4 weeks.

Main reasons for not taking part

  • Allergy to adhesives (sticky materials, like on the wearable patch)
  • Unable to cooperate with the study plan
  • Antibiotics taken in the past 4 weeks
  • A diagnosis of an inflammatory gut disorder

The registry criteria, word for word

Show all 16 criteriaShow less

Who can take part

  • Cases:
  • Males and females age 8 - 18 years
  • Diagnosis of irritable bowel syndrome (IBS)
  • Parental/guardian permission (informed consent) and child assent; Controls:
  • Males and Females age 8-18 years
  • No diagnosis of abdominal pain disorder
  • Parental/guardian permission (informed consent) and child assent

Who cannot take part

  • Allergy to adhesives
  • Inflammatory gastrointestinal disorder diagnosis; Controls:
  • Allergy to adhesives
  • Inflammatory gastrointestinal disorder diagnosis
  • Cases:
  • Inability to cooperate with study design
  • Antibiotic intake in the past 4 weeks
  • Inability to cooperate with study design
  • Antibiotic intake in the past 4 weeks

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 8 and 18 years old?

Where in United States

  • Children's Hospital of PhiladelphiaPhiladelphia, United StatesContact: Alain Benitez, MD, MSTRTaking people

About the trial

What the trial wants to find out

The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help each child with IBS feel better. The main question it aims to answer is:

Read full original descriptionShow less

1. What types of food do the kids eat and how do these diets relate to their symptoms? 2. Is there any motility pattern that we can identify from the kids with or without IBS using a wearable patch? 3. What kinds of bacteria and chemicals are found in the gut and urine of children with IBS, and how are these linked to their IBS symptoms?

Participants will use the wearable patch, answer questionnaires, collect stool and urine samples, and recall their 24 hours dietary.

The 2 groups in the trial

  • IBS Cohort

    Participants ages 8 to 18 years old who meet Rome IV diagnostic criteria for IBS

    Treatment: Wireless Patch System

  • Control Cohort

    Participants ageds 8-18 years old who don't have IBS

    Treatment: Wireless Patch System

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Role of Diet and Gastrointestinal Motility in Irritable Bowel Syndrome (IBS)
Plain-language title
How Diet and Gut Movement Relate to Symptoms in Children With Irritable Bowel SyndromeGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Fit questions
Built from NCT07283341, who can take part
Record updated
15 December 2025