Sensorimotor Integration in Patients With Tourette Syndrome
Key facts
- Who runs it
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
- Where
- Italy1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 60 people enrolled
- Started
- 20 Mar 2025
- Ended
- 3 Dec 2025
- Type of study
- Observational, 2 groups
- Record updated
- 18 December 2025
Who can take part
- Age
- 18 years to 65 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 13 criteriaShow less
Who can take part
- For Tourette Syndrome group:
- Clinical diagnosis of Tourette Syndrome (TS) according to DSM-5 criteria
- Age between 18 and 65 years
- Ability to understand and comply with study procedures
- Written informed consent provided; For Healthy Control group:
- No current or past history of neurological or psychiatric disorders
- Age between 18 and 65 years
- Matched to the TS group for age, sex, and education level
- Ability to understand and comply with study procedures
- Written informed consent provided
Who cannot take part
- History of significant neurological disorders (e.g., brain injury or dementia) or major psychiatric disorders (with the exception of conditions commonly associated with Tourette Syndrome, such as Obsessive-Compulsive Disorder, ADHD, depression, and anxiety)
- Failure or refusal to provide written informed consent
- Confirmed pregnancy (self-reported) and/or breastfeeding
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The present study investigates the mechanisms underlying the sense of agency in patients with Tourette Syndrome (TS). Previous research has shown that individuals with TS display impairments in both explicit and implicit aspects of agency, possibly due to altered integration between sensory feedback and motor predictions. To explore this hypothesis, the study will examine the phenomenon of sensory attenuation, a marker of sensorimotor integration that has not yet been investigated in this population. Furthermore, the study will assess how alterations in sensorimotor integration are related to the severity of TS symptoms.
The 2 groups in the trial
- Tourette Syndrome Patients
Patients affected by Tourette Syndrome
- Healthy controls
Individuals without neurological or psychiatric disorders
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Sensorimotor Integration in Patients With Tourette Syndrome: an Observational Study.
- Record updated
- 18 December 2025