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Brain Stimulation to Improve Movement in Progressive Supranuclear Palsy and Parkinson's Disease

Tests gentle electrical brain stimulation during walking practice in people with movement-affecting brain diseases.

Plain-language title generated from the registry record
Registry title: tDCS as Treatment for Motor Function

Key facts

Where
Toronto, CanadaSee the site

Where in Canada

  • Baycrest Academy of Health Sciences and Geriatric ResearchToronto, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Baycrest
Trial code
NCT07291687
Record updated
18 December 2025
Original description
Previous preliminary results are sufficiently impressive to suggest that tDCS stimulation does have the potential to improve motor function when that ability is trained during stimulation. In the proposed study, the investigation will assess whether walking sessions combined with tDCS lead to improvements in motor function: gait, articulation, eye gaze, and motor dexterity. In addition, the investigators wish to examine if such results can be replicated in people with other conditions, such as cortical basal syndrome, and Parkinson's disease.Read full original descriptionShow less

Transcranial Direct Current Stimulation as a Treatment for Motor Function in Participants Living With Progressive Supranuclear Palsy, Corticalbasal Syndrome Degeneration, or Parkinson's Disease

Previous preliminary results are sufficiently impressive to suggest that tDCS stimulation does have the potential to improve motor function when that ability is trained during stimulation. In the proposed study, the investigation will assess whether walking sessions combined with tDCS lead to improvements in motor function: gait, articulation, eye gaze, and motor dexterity. In addition, the investigators wish to examine if such results can be replicated in people with other conditions, such as cortical basal syndrome, and Parkinson's disease.

Inclusion: 1. Participants must be able to walk unassisted, or with the assistance of a walker or cane, and be individuals who walk daily; Participants should have a sufficient level of English to be able to express themselves verbally, be able to read and follow instructions.

Exclusion: 3. Individuals with metal implants within the brain such as shunts will be excluded.

ClinicalTrials.gov NCT07291687