Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway
Key facts
- Who runs it
- Duzce University
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 98 people enrolled
- Started
- 10 Nov 2025
- Ended
- 10 Mar 2026
- Type of study
- Observational, 2 groups
- Record updated
- 20 October 2026
Who can take part
- Age
- 18 years to 45 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Pregnant women scheduled for elective cesarean section
- Age between 18 and 45 years
- ASA physical status I-II
- No contraindication to spinal anesthesia
- Accepted for VR equipment usage during operation
- Signed written informed consent
Who cannot take part
- History of psychiatric or neurological disease
- Visual or auditory impairment
- Severe preeclampsia, eclampsia, or HELLP syndrome
- History of convulsions or epilepsy
- Anticipated need for postoperative intensive care unit (ICU) admission
- Perinatal loss (postpartum neonatal death)
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The research will be conducted as a prospective, observational, and comparative study with 98 pregnant volunteers aged 18-45 at Düzce University Faculty of Medicine. Participants will be divided into a VR group and a control group. Data will be collected using STAI-I, EPDS, NRS scales, and biochemical analyses (tryptophan, kynurenine, etc.).
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Upon completion, the project is expected to contribute to non-pharmacological approaches and new care protocols for reducing postpartum depression.
The 2 groups in the trial
- Group 1 (VR group, n = 49):
Patients who underwent cesarean section under spinal anesthesia and received intraoperative virtual reality (VR) intervention via a VR headset to provide sensory modulation.
- Group 2 (Control group, n = 49)
Patients who underwent cesarean section under spinal anesthesia and received standard clinical care without any VR application
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Observation of the Effects of Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression, Cognitive Function, and the Kynurenine Pathway
- Record updated
- 20 October 2026