Cognitive behavior therapy for people with repeated episodes of major depression
Tests cognitive behavior therapy against usual treatment in people with recurring major depression.
Plain-language title generated from the registry record
Registry title: Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.
Key facts
- Where
- Faisalabad, PakistanSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 50 with major depressive disorder who have had multiple episodes and moderate depression on a questionnaire.
- Age
- 18 to 50 years (the record lists the unit as weeks, which looks like a mistake).
- Sex
- All sexes can join.
- Disease stage
- Major depressive disorder (DSM 5 TR criteria) with multiple episodes, and moderate severity on the patient health questionnaire scale.
Main reasons for not taking part
- Under 18 or over 50 years
- Any other physical, psychiatric, or psychological condition
- Does not meet DSM 5 TR major depressive disorder criteria
- Mild, minimal, moderately severe, or severe score on the patient health questionnaire
Read by machine on 12 November 2026.
Where in Pakistan
- Government College University FaisalabadFaisalabad, PakistanContact: Qasir AbbasNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Government College University Faisalabad
- Trial code
- NCT07300527
- Record updated
- 23 December 2025
- Original description
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life, and meta memory and meta cognitive functioning after using Adapted CBT. Enhance emotional regulation by helping patients identify and modify maladaptive emotional responses, thereby reducing emotional reactivity and promoting healthier coping strategies. Strengthen relapse prevention skills by equipping patients with long-term cognitive and behavioral techniques to recognize early warning signs and apply learned strategies proactively to prevent future episodes. This research would be helpful for patients etc.Read full original descriptionShow less
Cognitive Behavior Therapy for Dysfunctional Cognitive and Behavioral Patterns and Functional Outcomes Among Patients With Major Depressive Disorder-Multiples Episodes: Randomized Control Trial.
The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life, and meta memory and meta cognitive functioning after using Adapted CBT. Enhance emotional regulation by helping patients identify and modify maladaptive emotional responses, thereby reducing emotional reactivity and promoting healthier coping strategies. Strengthen relapse prevention skills by equipping patients with long-term cognitive and behavioral techniques to recognize early warning signs and apply learned strategies proactively to prevent future episodes. This research would be helpful for patients etc.
Inclusion: Age range: 18-50 years No physical, psychiatric, or psychological conditions. patients who meet multiple Episodes. who meet DSM 5 TR Major Depressive Disorder Criteria. patients who meet moderate severity at patient health questionnaire scale .
Exclusion: age range: below 18 and above 50 years. presence of any physical, psychiatric, or psychological conditions. who do not meet DSM 5 TR Major Depressive Disorder Criteria. range at patient health questionnaire scale is mild , minimal or severe or moderately severe.