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Laser treatment tested in Asian adults with normal tension glaucoma

Tests a laser eye treatment, DSLT, in Asian adults with normal tension glaucoma.

Plain-language title generated from the registry record
Registry title: DSLT in Normal Tension Glaucoma (NTG) Asian Eyes

Key facts

Where
San Jose, United StatesSee the site

Where in United States

  • Ngoc Nguyen M.D.San Jose, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Ngoc Nguyen Inc.
Trial code
NCT07300852
Record updated
24 December 2025
Original description
The goal of this clinical trial is to evaluate the efficacy of direct selective laser trabeculoplasty (DSLT) or laser treatment in Asian patients with normal tension glaucoma. The main question it aims to answer is:Read full original descriptionShow less

The Effectiveness of DSLT in Asian Normal Tension Glaucoma Patients

The goal of this clinical trial is to evaluate the efficacy of direct selective laser trabeculoplasty (DSLT) or laser treatment in Asian patients with normal tension glaucoma. The main question it aims to answer is:

Does the DSLT reduce intraocular pressure (IOP) and medication use in Asian NTG subjects? Participants will attend routine follow-up visits with their eye surgeon and glaucoma testing such as optical coherence tomography (OCT) imaging and visual field test(s) after the laser study treatment.

Inclusion: Asian descent; NTG diagnosis: glaucomatous optic neuropathy in patients with IOP measurements consistently lower than 21 mmHg; Mean deviation (MD) of the visual field between 0 to -12dB; No significant central vision loss within 5 degrees within 5th percentile; Age ≥20 years; NTG patients who are medically controlled on 1-3 medications and safe to wash out or IOP is still insufficient from medications and safe to washout; Shaffer grade II or more on 3 of the 4 quadrants; Central corneal thickness (CCT) 450-600µm; All participants are able to provide written informed consent before participation.

Exclusion: Patients anticipating cataract surgery during the study follow-up period; History of SLT within last 2 years; History intraocular surgery including refractive surgery, except for history of cataract surgery that has been greater than 1 year; Any presence of relevant ocular diseases including retinal disease with no confirmed cure; Angle closure glaucoma or narrow angle status post laser peripheral iridotomy (LPI), or any other open angle glaucoma excluding NTG; Unable to have DSLT procedure due to pre-limbal findings.

ClinicalTrials.gov NCT07300852