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Predictive Factors of Complete Response to Immunotherapy in Metastatic Melanoma: a Single-center Retrospective Study Between 2013 and 2021

Key facts

Where
Strasbourg, FranceSee the site

Where in France

  • Service de dermatologie - Réanimation - CHU de Strasbourg - FranceStrasbourg, FranceTaking people

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Trial details

Who runs it
University Hospital, Strasbourg, France
Trial code
NCT07302607
Record updated
24 December 2025
Original description
Although impressive progress has been made with this new therapeutic strategy, only a proportion of patients achieve a complete and sustained response. Studies have already identified predictive factors of treatment response that are now widely recognized. In this study, the investigators aim to identify other response factors not yet evaluated in the literature.Read full original descriptionShow less

Although impressive progress has been made with this new therapeutic strategy, only a proportion of patients achieve a complete and sustained response. Studies have already identified predictive factors of treatment response that are now widely recognized. In this study, the investigators aim to identify other response factors not yet evaluated in the literature.

Inclusion: Age ≥ 18 years; Unresectable stage III or stage IV melanoma according to the AJCC classification - 8th edition; Curative immunotherapy treatment (anti-PD-1 and/or anti-CTLA-4); Treatment and follow-up at the Dermatology Department of the Strasbourg University Hospitals; Immunotherapy initiated between January 1, 2013, and December 31, 2021.

Exclusion: Adjuvant-intent immunotherapy; Less than 3 months of follow-up after the start of immunotherapy; Primary choroidal melanoma; Change of treatment before the first reassessment; Treatment and follow-up at a department other than the Dermatology Department of the Strasbourg University Hospitals.

ClinicalTrials.gov NCT07302607