Computer Planning to Define Safe Surgical Margins in Jaw Ameloblastoma
Tests computer-guided surgical planning to remove ameloblastoma of the lower jaw.
Plain-language title generated from the registry record
Registry title: Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin
Key facts
- Where
- Alexandria, EgyptSee the site
Where in Egypt
- Faculty of Dentistry, Alexandria UniversityAlexandria, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Alexandria University
- Trial code
- NCT07306962
- Record updated
- 29 December 2025
- Original description
Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.Read full original descriptionShow less
Does Computer-assist Virtual Lesion Segmentation Ushers to a Change in the Literature Consensus Regarding Mandibular Ameloblastoma Radiographic Safety Margin?. A Clinical Case Series
Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.
Inclusion: Patients with histologically confirmed ameloblastoma using a preoperative biopsy; Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.
Exclusion: Patients with recurrent lesion after resection; Patients with an active infection at the site of resection; Patients with lateral segmental mandibular defect involving the condyle.