Exercise effects on blood and fitness in people with overweight or obesity
Tests treadmill high-intensity interval training in adults aged 25 to 45 with overweight or obesity.
Plain-language title generated from the registry record
Registry title: Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals
Key facts
- Where
- Mueang Samut Prakan, ThailandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 25 and 45 years old?
Source: NCT07312344, who can take part
Where in Thailand
- Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi HospitalMueang Samut Prakan, ThailandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mahidol University
- Trial code
- NCT07312344
- Record updated
- 31 December 2025
- Original description
This project aims to study the effect of exercise in the obesity/overweight on the changes of physical fitness and blood components. This will provide novel knowledge for medical staffs, researchers, or companies developing alternative strategies for treating obesity/overweight, including drug development and health promotion project to delay or prevent the onset of the disease.Read full original descriptionShow less
Exploring the Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals on Lymphangiogenesis
This project aims to study the effect of exercise in the obesity/overweight on the changes of physical fitness and blood components. This will provide novel knowledge for medical staffs, researchers, or companies developing alternative strategies for treating obesity/overweight, including drug development and health promotion project to delay or prevent the onset of the disease.
Inclusion: Male or female individuals aged between 25-45 years; Thai nationality; Ability to walk or perform daily activities independently, without the use of an assistive device; Body mass index (BMI) between 25-35 kg/m²; Low physical activity levels or sedentary lifestyle based on the World Health Organization 2020; The levels of moderate-intensity physical activity < 150-300 minutes per week or the levels of vigorous-intensity physical activity < 75-150 minutes per week; Moderate-intensity physical activity: fast walking and bicycling. Vigorous-intensity physical activity: running, aerobic dance, and swimming All participants are required to meet all inclusion criteria to be eligible for the research project.
Exclusion: History of previous lower limb surgery, such as hip, knee, or ankle replacement; History of respiratory diseases, such as asthma, emphysema, or chronic obstructive pulmonary disease; History of cardiovascular diseases, such as coronary heart disease, aortic disease, arrhythmia, or deep vein thrombosis; History of high blood pressure (hypertension); History of vestibular system diseases, such as Meniere's disease or otitis media; History of neurological disease, such as severe Parkinson's disease or stroke; History of musculoskeletal diseases, such as severe osteoarthritis; History of severe brain disease, such as dementia; Severe visual or hearing impairment; Have a cognitive and comprehensive impairment and unable to complete the intervention; Smoking, substance abuse, or alcohol addiction; Have high physical activity or regularly exercise.