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Taurine supplement and blood vessel function in people with Long COVID

Looks at taurine's effect on blood vessels and standing responses in Long COVID.

Key facts

Who runs it
York University
Where
Toronto, CanadaSee the site
Trial code
Registry title
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Status
Recruiting
People taking part
30 people, planned
Started
1 Jun 2026
Expected to end
31 Dec 2027
Type of study
Observational, 2 groups
Treatments tested
  • Taurine supplementation
Record updated
5 June 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 18 to 65 who have had Long COVID symptoms for at least 3 months. They would take taurine for 12 weeks.

Age
18 to 65 years
Sex
All sexes can join.
Disease stage
Long COVID symptoms after infection for at least 3 months.

Main reasons for not taking part

  • Cannot do tilt table testing for 5 minutes
  • Cannot travel from home to York University
  • Cannot speak English or bring a translator
  • Blood clotting disorders

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • Participants will have had symptoms of Long COVID post-infection for at least 3 months

Who cannot take part

  • Blood clotting disorders
  • Inability to undergo tilt table testing for 5 minutes
  • Inability to transport selves to York University from their homes
  • Inability to speak English, or provide a translator

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Where in Canada

  • York UniversityToronto, CanadaContact: Heather EdgellTaking people

About the trial

What the trial wants to find out

Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC. Cost-effective and accessible interventions are needed to improve welfare and reduce healthcare costs. We will investigate the efficacy of 12-weeks of taurine supplementation (self-administered), on vascular function and the cardio/cerebrovascular responses to upright posture. We will measure resting vascular function with an EndoPAT device, resting heart rate variability, and the blood pressure, heart rate, and brain blood flow responses to 5 minutes of head-up tilt before and after weeks of taurine supplementation in LC. We hypothesize that the 12 weeks of supplementation will improve both resting vascular function and the responses to upright tilt. In turn, we hypothesize that symptoms will also improve (as measured by questionnaires).

The 2 groups in the trial

  • Taurine supplementation

    Long COVID patients will self-administer 12-wks of taurine supplementation

  • Time control

    Long COVID patients who are not taking taurine supplementation

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Plain-language title
Taurine supplement and blood vessel function in people with Long COVIDGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Fit questions
Built from NCT07312409, who can take part
Record updated
5 June 2026