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Predicting Pain Relief From Surgery for Endometriosis

Studies whether brain scans can predict pain relief from surgery for severe endometriosis.

Plain-language title generated from the registry record
Registry title: Predicting the Pain Outcome of Surgery for Endometriosis

Key facts

Where
Oxford, United KingdomSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 50 years old?

Source: NCT07313345, who can take part

Where in United Kingdom

  • Oxford University Hospitals Foundation TrustOxford, United KingdomTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of Oxford
Trial code
NCT07313345
Record updated
31 December 2025
Original description
This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis. The investigators will use brain imaging to explore this, as it allows meaningful results from a smaller sample of people than if questionnaires alone were relied on.Read full original descriptionShow less

Predicting the Pain Outcome of Surgery for Endometriosis

This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis. The investigators will use brain imaging to explore this, as it allows meaningful results from a smaller sample of people than if questionnaires alone were relied on.

Inclusion: willing and able to give informed consent; aged between 18 and 50 years of age; female or born female; diagnosed with stage III or IV endometriosis by scan (MRI or USS) or previous surgery; surgical treatment of severe endometriosis planned (surgical procedure at discretion of operating surgeon); reports pelvic pain of ≥4/10 (measured using a 0 - 10 numerical rating scale asking about the participant's worst pelvic pain associated with their endometriosis); reasonably fluent in English; in the Investigator's opinion, is able and willing to comply with all study requirements; willing to allow his or her General Practitioner and consultant to be notified of participation in the study.

Exclusion: pregnant, lactating or planning pregnancy during the course of the study; contraindication to MRI.

ClinicalTrials.gov NCT07313345