Under construction – not a live service
Sign in
Taking people in EthiopiaNo phase

Video lessons and text reminders for household contacts of tuberculosis patients

Tests video education and text reminders for close contacts of tuberculosis patients.

Plain-language title generated from the registry record
Registry title: Digital Health Intervention to Improve TPT Uptake

Key facts

Where
Arba Minch, Birbir, Chencha, Felege Neway, and Laha, EthiopiaSee the 14 sites

Where in Ethiopia

  • Arba Minch General Hospital and Dilfana Primary HospitalArba Minch, EthiopiaNo longer taking part
  • Chano Health centerArba Minch, EthiopiaNo longer taking part
  • Gerese Primary HospitalArba Minch, EthiopiaNo longer taking part
  • Shelle Health centerArba Minch, EthiopiaNo longer taking part
  • Birbir Primary HospitalBirbir, EthiopiaNo longer taking part
  • Chencha Generl HospitalChencha, EthiopiaTaking people
  • Zadha Health centerChencha, EthiopiaTaking people
  • Bulki Health centerFelege Neway, EthiopiaTaking people
  • Dombe Health centerFelege Neway, EthiopiaTaking people
  • Galma Health centerFelege Neway, EthiopiaTaking people
  • Lotte Health centerFelege Neway, EthiopiaTaking people
  • Sawla General Hospital and Sawla Health CenterFelege Neway, EthiopiaTaking people
  • Shefite Health centerFelege Neway, EthiopiaTaking people
  • Laha Primary HospitalLaha, EthiopiaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Arba Minch University
Trial code
NCT07313995
Record updated
25 September 2026
Original description
Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population. Specifically, tuberculosis in children and newly diagnosed TB cases show there is current transmission of TB; to reduce this transmission and to attain the end TB strategy, preventing household TB transmission plays a great role. However, initiation and completion of TB preventive therapy (TPT) among close contacts of index TB patients are suboptimal. Some of the identified factors of low TPT initiation and completion are insufficient patient education, inadequate understanding of TPT, health professionals' perception, parental knowledge, and belief. The digital health intervention is currently being studied as a suggested health intervention that improves the utilization of health care services, including treatment adherence. A systematic review shows that TB treatment outcomes improved with the use of patient education, counseling, text reminders, and digital health technologies. However, other literature indicates controversial results, including our systematic review result, which identified that video directly observed therapy and text message (digital intervention) have no significant effect on TPT completion. In addition, the studies are scarce; therefore, this study aims to assess the effect of video-based education intervention combined with text message reminder (digital health intervention) in improving the initiation and completion of TPT among close contacts of drug-sensitive pulmonary TB patients in South Ethiopia.Read full original descriptionShow less

Digital Health Intervention in Improving Preventive Treatment Initiation and Completion Among Close Contacts of Tuberculosis Patients in South Ethiopia

Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population. Specifically, tuberculosis in children and newly diagnosed TB cases show there is current transmission of TB; to reduce this transmission and to attain the end TB strategy, preventing household TB transmission plays a great role. However, initiation and completion of TB preventive therapy (TPT) among close contacts of index TB patients are suboptimal. Some of the identified factors of low TPT initiation and completion are insufficient patient education, inadequate understanding of TPT, health professionals' perception, parental knowledge, and belief. The digital health intervention is currently being studied as a suggested health intervention that improves the utilization of health care services, including treatment adherence. A systematic review shows that TB treatment outcomes improved with the use of patient education, counseling, text reminders, and digital health technologies. However, other literature indicates controversial results, including our systematic review result, which identified that video directly observed therapy and text message (digital intervention) have no significant effect on TPT completion. In addition, the studies are scarce; therefore, this study aims to assess the effect of video-based education intervention combined with text message reminder (digital health intervention) in improving the initiation and completion of TPT among close contacts of drug-sensitive pulmonary TB patients in South Ethiopia.

The study hypothesizes that digital health intervention for close contacts of index drug-sensitive pulmonary TB patients will lead to higher TPT initiation and completion rates than standard care.

Inclusion: All household and close contacts of drug-sensitive pulmonary TB patients; Living in the catchment area of the selected health facility; Willing to stay for at least 4 months in the catchment area.

Exclusion: Close contacts with drug-resistant TB; Individuals with a known allergy to TPT drugs or those contraindicated for TPT drugs; Close contacts screened as symptomatic for TB; Temporary residents staying for less than 4 months.

ClinicalTrials.gov NCT07313995