Iron Supplements and Blood Sugar Handling in Women With Overweight or Obesity
Tests two iron doses on insulin and glucose in women with overweight or obesity.
Plain-language title generated from the registry record
Registry title: The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
Key facts
- Where
- Beirut, LebanonSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT07315282, who can take part
Where in Lebanon
- American University of BeirutBeirut, LebanonTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nicole Stoffel
- Trial code
- NCT07315282
- Record updated
- 2 January 2026
- Original description
The study will be a randomized, double-blind, 17-day metabolic intervention trial including 14 days of high-dose or low-dose iron supplementation. A total of 70 overweight or obese (OW/OB) women will be enrolled. Participants will be individually randomized into either the high-iron or low-iron group.Read full original descriptionShow less
The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
The study will be a randomized, double-blind, 17-day metabolic intervention trial including 14 days of high-dose or low-dose iron supplementation. A total of 70 overweight or obese (OW/OB) women will be enrolled. Participants will be individually randomized into either the high-iron or low-iron group.
Women in the low-iron group will receive 15 mg of iron as ferrous fumarate daily for 14 days, while women in the high-iron group will receive 195 mg of iron as ferrous sulfate daily for 14 days.
The study consists of three visits in total. On Day 0, a fasting blood sample will be collected and an OGTT will be performed, with additional blood samples collected at 1 hour and 2 hours post-OGTT. The OGTT will be repeated on Day 14, after 14 days of oral iron supplementation, and again on Day 17, four days after oral iron supplementation has been stopped
Inclusion: BMI ≥ 27.5 kg/m2; serum ferritin <30 μg/L; hemoglobin ≥ 11 g/dl; fasting blood glucose < 5.6 mmol/L.
Exclusion: medical disorders are known to affect iron absorption or metabolism, or T2DM; intravenous or high dose oral iron in the preceding 2 months; cigarette smoking; recent blood transfusion or major blood loss.